m6A methylation: Critical roles in aging and neurological diseases
Y Fan, X Lv, Z Chen, Y Peng, M Zhang - Frontiers in Molecular …, 2023 - frontiersin.org
N6-methyladenosine (m6A) is the most abundant internal RNA modification in eukaryotic
cells, which participates in the functional regulation of various biological processes. It …
cells, which participates in the functional regulation of various biological processes. It …
Neurosteroids: A novel promise for the treatment of stroke and post‐stroke complications
J Xu, Y Zhou, C Yan, X Wang, J Lou… - Journal of …, 2022 - Wiley Online Library
Stroke is the primary reason for death and disability worldwide, with few treatment strategies
to date. Neurosteroids, which are natural molecules in the brain, have aroused great interest …
to date. Neurosteroids, which are natural molecules in the brain, have aroused great interest …
TNF-α impairs pericyte-mediated cerebral microcirculation via the NF-κB/iNOS axis after experimental traumatic brain injury
S Zheng, C Wang, L Lin, S Mu, H Liu, X Hu… - Journal of …, 2023 - liebertpub.com
Secondary structural and functional abnormalities of the neurovascular unit are important
pathological mechanisms following traumatic brain injury (TBI). The neurovascular unit …
pathological mechanisms following traumatic brain injury (TBI). The neurovascular unit …
Dysfunction of ABC transporters at the surface of BBB: potential implications in intractable epilepsy and applications of nanotechnology enabled drug delivery
Epilepsy is a chronic neurological disorder affecting 70 million people globally. One of the
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury
W Tang, ZD Guo, WN Chai, DL Du… - Neural Regeneration …, 2022 - journals.lww.com
Abstract MicroRNA-491-5p (miR-491-5p) plays an important role in regulating cell
proliferation and migration; however, the effect of miR-491-5p on neovascularization after …
proliferation and migration; however, the effect of miR-491-5p on neovascularization after …
Will sirtuins be promising therapeutic targets for TBI and associated neurodegenerative diseases?
Q Yang, Y Zhou, Y Sun, Y Luo, Y Shen… - Frontiers in …, 2020 - frontiersin.org
Traumatic brain injury (TBI), a leading cause of morbidity worldwide, induces mechanical,
persistent structural, and metabolic abnormalities in neurons and other brain-resident cells …
persistent structural, and metabolic abnormalities in neurons and other brain-resident cells …
Neuroprotective effect of physical activity in ischemic stroke: Focus on the neurovascular unit
H Zhang, Q **e, J Hu - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Cerebral ischemia is one of the major diseases associated with death or disability among
patients. To date, there is a lack of effective treatments, with the exception of thrombolytic …
patients. To date, there is a lack of effective treatments, with the exception of thrombolytic …
Nerve growth factor promotes retinal neurovascular unit repair: a review
B Li, B Ning, F Yang, C Guo - Current Eye Research, 2022 - Taylor & Francis
Purpose: The purpose of this paper is to investigate how the imbalance of neurogenic factor
(NGF) and its precursor (pro-NGF) mediates structural and functional impairment of retinal …
(NGF) and its precursor (pro-NGF) mediates structural and functional impairment of retinal …
Differential leukocyte and platelet profiles in distinct models of traumatic brain injury
Traumatic brain injury (TBI) affects over 3 million individuals every year in the US There is
growing appreciation that TBI can produce systemic modifications, which are in part …
growing appreciation that TBI can produce systemic modifications, which are in part …
Human hippocampal astrocytes: Computational dissection of their transcriptome, sexual differences and exosomes across ageing and mild‐cognitive impairment
DV Guebel - European Journal of Neuroscience, 2023 - Wiley Online Library
The role of astrocytes in Alzheimer's disease is often disregarded. Hence, characterization of
astrocytes along their early evolution toward Alzheimer would be greatly beneficial …
astrocytes along their early evolution toward Alzheimer would be greatly beneficial …