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[HTML][HTML] Bile acids, intestinal barrier dysfunction, and related diseases
The intestinal barrier is a precisely regulated semi-permeable physiological structure that
absorbs nutrients and protects the internal environment from infiltration of pathological …
absorbs nutrients and protects the internal environment from infiltration of pathological …
An overview of drug delivery nanosystems for sepsis-related liver injury treatment
Y Lu, Y Shi, Q Wu, X Sun, WZ Zhang… - International Journal of …, 2023 - Taylor & Francis
Sepsis, which is a systemic inflammatory response syndrome caused by infection, has high
morbidity and mortality. Sepsis-related liver injury is one of the manifestations of sepsis …
morbidity and mortality. Sepsis-related liver injury is one of the manifestations of sepsis …
Infections in burn patients
JL Kiley, DG Greenhalgh - Surgical Clinics, 2023 - surgical.theclinics.com
Infections are the leading cause of mortality in burn patients who survive initial resuscitation
1, 2 and present diagnostic and therapeutic challenges. 3 Here, the authors discuss the role …
1, 2 and present diagnostic and therapeutic challenges. 3 Here, the authors discuss the role …
Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy
Intestinal barrier derangement allows intestinal bacteria and their products to translocate to
the systemic circulation. Pseudomonas aeruginosa (PA) superimposed infection in critically …
the systemic circulation. Pseudomonas aeruginosa (PA) superimposed infection in critically …
[HTML][HTML] Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice
D Wu, S Su, X Zha, Y Wei, G Yang, Q Huang, Y Yang… - Redox Biology, 2023 - Elsevier
Mucus forms the first line of defence of the intestinal mucosa barrier, and mucin is its core
component. Glutamine is a vital energy substance for goblet cells; it can promote mucus …
component. Glutamine is a vital energy substance for goblet cells; it can promote mucus …
Role of intestinal alkaline phosphatase in innate immunity
SB Singh, HC Lin - Biomolecules, 2021 - mdpi.com
Intestinal alkaline phosphatase (IAP) is a multi-functional protein that has been
demonstrated to primarily protect the gut. The role of IAP in maintaining intestinal …
demonstrated to primarily protect the gut. The role of IAP in maintaining intestinal …
Protective properties of intestinal alkaline phosphatase supplementation on the intestinal barrier: interactions and effects
C Gao, MY Koko, W Hong, J Gankhuyag… - Journal of Agricultural …, 2023 - ACS Publications
The intestinal barrier is critical for maintaining intestinal homeostasis, and its dysfunction is
associated with various diseases. Recent findings have revealed the multifunctional role of …
associated with various diseases. Recent findings have revealed the multifunctional role of …
Interconnections of Pseudomonas aeruginosa quorum-sensing systems in intestinal permeability and inflammation
Quorum sensing (QS) is a highly conserved microbial communication mechanism based on
the production and sensing of secreted signaling molecules. The recalcitrant pathogen …
the production and sensing of secreted signaling molecules. The recalcitrant pathogen …
[HTML][HTML] Kinetics of inflammatory mediators in the immune response to burn injury: Systematic review and meta-analysis of animal studies
PPG Mulder, CR Hooijmans, M Vlig… - Journal of Investigative …, 2024 - Elsevier
Burns are often accompanied by a dysfunctional immune response, which can lead to
systemic inflammation, shock, and excessive scarring. The objective of this study was to …
systemic inflammation, shock, and excessive scarring. The objective of this study was to …
Targeting the intestinal barrier to prevent gut-derived inflammation and disease: A role for intestinal alkaline phosphatase
F Kühn, R Duan, M Ilmer, U Wirth, F Adiliaghdam… - Visceral …, 2021 - karger.com
Background: Intestinal alkaline phosphatase (IAP) as a tissue-specific isozyme of alkaline
phosphatases is predominantly produced by enterocytes in the proximal small intestine. In …
phosphatases is predominantly produced by enterocytes in the proximal small intestine. In …