New applications of synthetic biology tools for cyanobacterial metabolic engineering

M Santos-Merino, AK Singh, DC Ducat - Frontiers in bioengineering …, 2019 - frontiersin.org
Cyanobacteria are promising microorganisms for sustainable biotechnologies, yet unlocking
their potential requires radical re-engineering and application of cutting-edge synthetic …

Circadian rhythms in cyanobacteria

SE Cohen, SS Golden - Microbiology and Molecular Biology …, 2015 - Am Soc Microbiol
Life on earth is subject to daily and predictable fluctuations in light intensity, temperature,
and humidity created by rotation of the earth. Circadian rhythms, generated by a circadian …

[HTML][HTML] An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver

K Zhu, IJ Celwyn, D Guan, Y **ao, X Wang, W Hu… - Molecular cell, 2023 - cell.com
Circadian gene transcription is fundamental to metabolic physiology. Here we report that the
nuclear receptor REV-ERBα, a repressive component of the molecular clock, forms circadian …

A hard day's night: cyanobacteria in diel cycles

DG Welkie, BE Rubin, S Diamond, RD Hood… - Trends in …, 2019 - cell.com
Cyanobacteria are photosynthetic prokaryotes that are influential in global geochemistry and
are promising candidates for industrial applications. Because the livelihood of cyanobacteria …

Synchronization of the circadian clock to the environment tracked in real time

M Fang, AG Chavan, A LiWang… - Proceedings of the …, 2023 - National Acad Sciences
The circadian system of the cyanobacterium Synechococcus elongatus PCC 7942 relies on
a three-protein nanomachine (KaiA, KaiB, and KaiC) that undergoes an oscillatory …

Structure, function, and mechanism of the core circadian clock in cyanobacteria

JA Swan, SS Golden, A LiWang, CL Partch - Journal of Biological …, 2018 - ASBMB
Circadian rhythms enable cells and organisms to coordinate their physiology with the cyclic
environmental changes that come as a result of Earth's light/dark cycles. Cyanobacteria …

Orchestration of circadian timing by macromolecular protein assemblies

CL Partch - Journal of molecular biology, 2020 - Elsevier
Genetically encoded biological clocks are found broadly throughout eukaryotes and in
cyanobacteria, where they generate circadian (about a day) rhythms that allow organisms to …

Daily cycles of reversible protein condensation in cyanobacteria

GK Pattanayak, Y Liao, EWJ Wallace, B Budnik… - Cell reports, 2020 - cell.com
An emerging principle of cell biology is the regulated conversion of macromolecules
between soluble and condensed states. To screen for such regulation of the cyanobacterial …

Light modulates the biosynthesis and organization of cyanobacterial carbon fixation machinery through photosynthetic electron flow

Y Sun, S Casella, Y Fang, F Huang, M Faulkner… - Plant …, 2016 - academic.oup.com
Cyanobacteria have evolved effective adaptive mechanisms to improve photosynthesis and
CO2 fixation. The central CO2-fixing machinery is the carboxysome, which is composed of …

A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues

TH Mann, W Seth Childers, JA Blair, MR Eckart… - Nature …, 2016 - nature.com
All cells must integrate sensory information to coordinate developmental events in space
and time. The bacterium Caulobacter crescentus uses two-component phospho-signalling to …