The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

With the aging population, prevalence of neurodegenerative diseases is increasing, thus
placing a growing burden on individuals and the whole society. However, individual rates of …

Accumulating research shows that prenatal exposure to maternal stress increases the risk
for behavioral and mental health problems later in life. This review systematically analyzes …

Telomere shortening to a critical length can trigger aging and shorter life spans in mice and
humans by a mechanism that involves induction of a persistent DNA damage response at …

Cellular senescence is a homeostatic biological process characterized by a permanent state
of cell cycle arrest that can contribute to the decline of the regenerative potential and …

The cellular senescence definition comes to the fact of cells irreversible proliferation
disability. Besides the cell cycle arrest, senescent cells go through some morphological …

Telomere attrition is considered a hallmark of ageing. Untangling the proximate causes of
telomere attrition may therefore reveal important aspects about the ageing process. In a …

The long-term consequences of exposure to excess stress, particularly during sensitive
developmental windows, on the initiation and progression of many complex, common …

Telomere length (TL) has become a biomarker of increasing interest within ecology and
evolutionary biology, and has been found to predict subsequent survival in some recent …