Impairment of the blood–brain barrier (BBB) integrity is implicated in the numerous
neurological disorders associated with neuroinflammation, neurodegeneration and aging. It …

Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …

Recent advances have contributed to a mechanistic understanding of neuroimmune
interactions in the intestine and revealed an essential role of this cross talk for gut …

Neuroimmune cross-talk participates in intestinal tissue homeostasis and host defense.
However, the matrix of interactions between arrays of molecularly defined neuron subsets …

Peripheral β-amyloid (Aβ), including those contained in the gut, may contribute to the
formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on …

Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

Background Remodeling eubiosis of the gut microenvironment may contribute to preventing
the occurrence and development of depression. Mounting experimental evidence has …

The brain and gut are intricately connected and respond to various stimuli. Stress-induced
brain-gut communication is implicated in the pathogenesis and relapse of gut disorders. The …

The gut microbiome is well known to impact host physiology and health. Given widespread
control of physiology by circadian clocks, we asked how the microbiome interacts with …

Amino acid availability is monitored by animals to adapt to their nutritional environment.
Beyond gustatory receptors and systemic amino acid sensors, enteroendocrine cells (EECs) …