New frontiers in time-domain diffuse optics, a review

A Pifferi, D Contini, AD Mora, A Farina… - … of biomedical optics, 2016‏ - spiedigitallibrary.org
The recent developments in time-domain diffuse optics that rely on physical concepts (eg,
time-gating and null distance) and advanced photonic components (eg, vertical cavity …

Diffuse optical characterization of collagen absorption from 500 to 1700 nm

SKV Sekar, I Bargigia, AD Mora… - … of biomedical optics, 2017‏ - spiedigitallibrary.org
Reduction in scattering, high absorption, and spectral features of tissue constituents above
1000 nm could help in gaining higher spatial resolution, penetration depth, and specificity …

Non-invasive investigation of adipose tissue by time domain diffuse optical spectroscopy

P Lanka, A Segala, A Farina… - Biomedical Optics …, 2020‏ - opg.optica.org
The human abdominal region is very heterogeneous and stratified with subcutaneous
adipose tissue (SAT) being one of the primary layers. Monitoring this tissue is crucial for …

Broadband time domain diffuse optical reflectance spectroscopy: a review of systems, methods, and applications

S Konugolu Venkata Sekar, P Lanka, A Farina… - Applied Sciences, 2019‏ - mdpi.com
This review presents recent developments and a wide overview of broadband time domain
diffuse optical spectroscopy (TD-DOS). Various topics including physics of photon migration …

In Vivo, Non-Invasive Characterization of Human Bone by Hybrid Broadband (600-1200 nm) Diffuse Optical and Correlation Spectroscopies

S Konugolu Venkata Sekar, M Pagliazzi, E Negredo… - PloS one, 2016‏ - journals.plos.org
Non-invasive in vivo diffuse optical characterization of human bone opens a new possibility
of diagnosing bone related pathologies. We present an in vivo characterization performed …

Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy

L Di Sieno, A Behera, S Rohilla, E Ferocino… - Biomedical Optics …, 2020‏ - opg.optica.org
Two main bottlenecks prevent time-domain diffuse optics instruments to reach their
maximum performances, namely the limited light harvesting capability of the detection chain …

Broadband diffuse optical characterization of elastin for biomedical applications

SKV Sekar, JS Beh, A Farina, A Dalla Mora, A Pifferi… - Biophysical …, 2017‏ - Elsevier
Elastin is a key structural protein of dynamic connective tissues widely found in the
extracellular matrix of skin, arteries, lungs and ligaments. It is responsible for a range of …

The use of supercontinuum laser sources in biomedical diffuse optics: unlocking the power of multispectral imaging

F Lange, L Giannoni, I Tachtsidis - Applied Sciences, 2021‏ - mdpi.com
Optical techniques based on diffuse optics have been around for decades now and are
making their way into the day-to-day medical applications. Even though the physics …

Characterization of bony anatomic regions in pediatric and adult healthy volunteers using diffuse optical spectroscopic imaging

HM Peterson, A Tank, DS Geller… - … of biomedical optics, 2020‏ - spiedigitallibrary.org
Significance: Diffuse optical spectroscopic imaging (DOSI) measures quantitative functional
and molecular information in thick tissue in a noninvasive manner using near-infrared light …