Not so spontaneous: Multi-dimensional representations of behaviors and context in sensory areas

L Avitan, C Stringer - Neuron, 2022 - cell.com
Sensory areas are spontaneously active in the absence of sensory stimuli. This
spontaneous activity has long been studied; however, its functional role remains largely …

Neural mechanisms that make perceptual decisions flexible

G Okazawa, R Kiani - Annual review of physiology, 2023 - annualreviews.org
Neural mechanisms of perceptual decision making have been extensively studied in
experimental settings that mimic stable environments with repeating stimuli, fixed rules, and …

Molecular convolutional neural networks with DNA regulatory circuits

X **ong, T Zhu, Y Zhu, M Cao, J **ao, L Li… - Nature Machine …, 2022 - nature.com
Complex biomolecular circuits enabled cells with intelligent behaviour to survive before
neural brains evolved. Since DNA computing was first demonstrated in the mid-1990s …

Mouse prefrontal cortex represents learned rules for categorization

S Reinert, M Hübener, T Bonhoeffer, PM Goltstein - Nature, 2021 - nature.com
The ability to categorize sensory stimuli is crucial for an animal's survival in a complex
environment. Memorizing categories instead of individual exemplars enables greater …

Posterior parietal cortex plays a causal role in perceptual and categorical decisions

Y Zhou, DJ Freedman - Science, 2019 - science.org
Posterior parietal cortex (PPC) activity correlates with monkeys' decisions during visual
discrimination and categorization tasks. However, recent work has questioned whether …

Primate superior colliculus is causally engaged in abstract higher-order cognition

B Peysakhovich, O Zhu, SM Tetrick, V Shirhatti… - Nature …, 2024 - nature.com
The superior colliculus is an evolutionarily conserved midbrain region that is thought to
mediate spatial orienting, including saccadic eye movements and covert spatial attention …

Emergence of cortical network motifs for short-term memory during learning

XW Chia, JK Tan, LF Ang, T Kamigaki… - Nature …, 2023 - nature.com
Learning of adaptive behaviors requires the refinement of coordinated activity across
multiple brain regions. However, how neural communications develop during learning …

[HTML][HTML] The mouse posterior parietal cortex: Anatomy and functions

D Lyamzin, A Benucci - Neuroscience research, 2019 - Elsevier
In recent years, the number of studies on decision-making in mice has increased
dramatically. Many of these studies focus on the posterior parietal cortex (PPC), an area that …

Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning

F Najafi, GF Elsayed, R Cao, E Pnevmatikakis… - Neuron, 2020 - cell.com
Inhibitory neurons, which play a critical role in decision-making models, are often simplified
as a single pool of non-selective neurons lacking connection specificity. This assumption is …

Synaptic wiring motifs in posterior parietal cortex support decision-making

AT Kuan, G Bondanelli, LN Driscoll, J Han, M Kim… - Nature, 2024 - nature.com
The posterior parietal cortex exhibits choice-selective activity during perceptual decision-
making tasks,,,,,,,,–. However, it is not known how this selective activity arises from the …