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Vitamin C in stem cell biology: impact on extracellular matrix homeostasis and epigenetics
Transcription factors and signaling molecules are well‐known regulators of stem cell identity
and behavior; however, increasing evidence indicates that environmental cues contribute to …
and behavior; however, increasing evidence indicates that environmental cues contribute to …
Effects of antioxidant supplements on the survival and differentiation of stem cells
S Shaban, MWA El-Husseny… - Oxidative Medicine …, 2017 - Wiley Online Library
Although physiological levels of reactive oxygen species (ROS) are required to maintain the
self‐renewal capacity of stem cells, elevated ROS levels can induce chromosomal …
self‐renewal capacity of stem cells, elevated ROS levels can induce chromosomal …
[HTML][HTML] Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications
SM Yuan, XT Yang, SY Zhang, WD Tian… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
For more than 20 years, researchers have isolated and identified postnatal dental pulp stem
cells (DPSCs) from different teeth, including natal teeth, exfoliated deciduous teeth, healthy …
cells (DPSCs) from different teeth, including natal teeth, exfoliated deciduous teeth, healthy …
Increasing efficiency of human mesenchymal stromal cell culture by optimization of microcarrier concentration and design of medium feed
AKL Chen, YK Chew, HY Tan, S Reuveny, SKW Oh - Cytotherapy, 2015 - Elsevier
Background aims Large amounts of human mesenchymal stromal cells (MSCs) are needed
for clinical cellular therapy. In a previous publication, we described a microcarrier-based …
for clinical cellular therapy. In a previous publication, we described a microcarrier-based …
[PDF][PDF] Role of signaling pathways in mesenchymal stem cell differentiation
Mesenchymal Stem Cells (MSCs) are self-renewing cells with ability to differentiate into
organized, functional network of cells. In recent past research in develo** clinical …
organized, functional network of cells. In recent past research in develo** clinical …
Vitamin C deficiency reduces neurogenesis and proliferation in the SVZ and lateral ventricle extensions of the young guinea pig brain
Although scurvy, the severe form of vitamin C deficiency, has been almost eradicated, the
prevalence of subclinical vitamin C deficiency is much higher than previously estimated and …
prevalence of subclinical vitamin C deficiency is much higher than previously estimated and …
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screening
G Chen, Y **n, MM Hammour, B Braun, S Ehnert… - Archives of …, 2024 - Springer
Drug toxicity is an important cause of chronic liver damage, which in the long term can lead
to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance …
to impaired bone homeostasis through an imbalance in the liver-bone axis. For instance …
Vitamin C induces periodontal ligament progenitor cell differentiation via activation of ERK pathway mediated by PELP1
The differentiation of periodontal ligament (PDL) progenitor cells is important for maintaining
the homeostasis of PDL tissue and alveolar bone. Vitamin C (VC), a water-soluble nutrient …
the homeostasis of PDL tissue and alveolar bone. Vitamin C (VC), a water-soluble nutrient …
Chondrogenic differentiation of Wharton's Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich …
In this research, hWJ-MSCs were grown on silk scaffolds and induced towards
chondrogenesis by supplementation with L-ascorbic acid (LAA) or platelet rich plasma …
chondrogenesis by supplementation with L-ascorbic acid (LAA) or platelet rich plasma …
Enhanced proliferation and differentiation of mesenchymal stem cells by astaxanthin-encapsulated polymeric micelles
J Zhang, CA Peng - PLoS One, 2019 - journals.plos.org
Astaxanthin is a highly potent antioxidant which can be extracted from Haematococcus
pluvialis when cultivated and induced at high stress conditions. Due to astaxanthin's …
pluvialis when cultivated and induced at high stress conditions. Due to astaxanthin's …