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Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria
During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD)
considering the disease as a continuum. Thanks to evolving biomarker research and …
considering the disease as a continuum. Thanks to evolving biomarker research and …
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
The genetic landscape of Alzheimer disease: clinical implications and perspectives
C Van Cauwenberghe, C Van Broeckhoven… - Genetics in …, 2016 - nature.com
The search for the genetic factors contributing to Alzheimer disease (AD) has evolved
tremendously throughout the years. It started from the discovery of fully penetrant mutations …
tremendously throughout the years. It started from the discovery of fully penetrant mutations …
Timely diagnosis for Alzheimer's disease: a literature review on benefits and challenges
B Dubois, A Padovani, P Scheltens… - Journal of …, 2015 - journals.sagepub.com
Background: Timely diagnosis of Alzheimer's disease (AD) refers to a diagnosis at the stage
when patients come to the attention of clinicians because of concerns about changes in …
when patients come to the attention of clinicians because of concerns about changes in …
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …
P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …
[書籍][B] Privileged structures in drug discovery: medicinal chemistry and synthesis
L Yet - 2018 - books.google.com
A comprehensive guide to privileged structures and their application in the discovery of new
drugs The use of privileged structures is a viable strategy in the discovery of new medicines …
drugs The use of privileged structures is a viable strategy in the discovery of new medicines …
Phytochemicals: a promising alternative for the prevention of Alzheimer's disease
Alzheimer's disease (AD) is a neurological condition that worsens with ageing and affects
memory and cognitive function. Presently more than 55 million individuals are affected by …
memory and cognitive function. Presently more than 55 million individuals are affected by …
2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase …
Purpose In the last decade, the research community has focused on defining reliable
biomarkers for the early detection of Alzheimer's disease (AD) pathology. In 2017, the …
biomarkers for the early detection of Alzheimer's disease (AD) pathology. In 2017, the …
Considerations regarding a diagnosis of Alzheimer's disease before dementia: a systematic review
J van der Schaar, LNC Visser, FH Bouwman… - Alzheimer's research & …, 2022 - Springer
Abstract Background The NIA-AA research framework proposes a purely biological
definition of Alzheimer's disease (AD). This implies that AD can be diagnosed based on …
definition of Alzheimer's disease (AD). This implies that AD can be diagnosed based on …
Alzheimer's disease in the Latino community: intersection of genetics and social determinants of health
Alzheimer's disease (AD) is the most common type of dementia among individuals 65 or
older. There are more than 5 million diagnosed cases in the US alone and this number is …
older. There are more than 5 million diagnosed cases in the US alone and this number is …