Ischemic heart disease is the greatest health burden and most frequent cause of death
worldwide. Myocardial ischemia/reperfusion is the pathophysiological substrate of ischemic …

Stroke and acute myocardial infarction are leading causes of mortality worldwide. The latter
accounts for approximately 9 million deaths annually. In turn, ischemic stroke is a significant …

Effective therapeutic strategies for myocardial ischemia/reperfusion (I/R) injury remain
elusive. Targeting reactive oxygen species (ROS) provides a practical approach to mitigate …

Despite impressive improvements in the care of patients with ST-segment elevation
myocardial infarction, mortality remains high. Reperfusion is necessary for myocardial …

The clinical treatments of maxillofacial bone defects pose significant challenges due to
complex microenvironments, including severe inflammation, high levels of reactive oxygen …

Myocardial ischemia-reperfusion injury (MIRI) is involved in the pathogenesis of multiple
cardiovascular diseases. This study elucidated the biological function of lysine …

Myocardial ischemia–reperfusion injury (MIRI) is fatal to patients, leading to cardiomyocyte
death and myocardial remodeling. Reactive oxygen species (ROS) and oxidative stress play …

Objective Limited treatments exist for nonoperative chronic coronary artery disease.
Previously, our laboratory has investigated extracellular vesicle (EV) therapy as a potential …

Oxidative stress driven by several environmental and local airway factors associated with
chronic obstructive bronchiolitis, a hallmark feature of COPD, plays a crucial role in disease …

The healthy human heart has special directional arrangement of cardiomyocytes and a
unique electrical conduction system, which is critical for the maintenance of effective …