Chemical ecology of antibiotic production by actinomycetes

A Van der Meij, SF Worsley… - FEMS microbiology …, 2017 - academic.oup.com
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural
products relevant for agriculture, biotechnology and medicine, including the majority of the …

Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era

HU Van Der Heul, BL Bilyk, KJ McDowall… - Natural product …, 2018 - pubs.rsc.org
Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis

K Li, S Chen, X Pang, J Cai, X Zhang, Y Liu… - European Journal of …, 2022 - Elsevier
The mangrove forests are a complex ecosystem, and the microbial communities in
mangrove sediments play a critical role in the biogeochemical cycles of mangrove …

Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes

RH Baltz - Journal of Industrial Microbiology and Biotechnology, 2016 - academic.oup.com
Actinomycetes continue to be important sources for the discovery of secondary metabolites
for applications in human medicine, animal health, and crop protection. With the maturation …

Strain-Level Diversity of Secondary Metabolism in Streptomyces albus

RF Seipke - PLoS one, 2015 - journals.plos.org
Streptomyces spp. are robust producers of medicinally-, industrially-and agriculturally-
important small molecules. Increased resistance to antibacterial agents and the lack of new …

Recent advances of marine sponge-associated microorganisms as a source of commercially viable natural products

TSM Amelia, FAC Suaberon, J Vad, ADM Fahmi… - Marine …, 2022 - Springer
Many industrially significant compounds have been derived from natural products in the
environment. Research efforts so far have contributed to the discovery of beneficial natural …

Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities

J Liu, X Zhu, SJ Kim, W Zhang - Natural product reports, 2016 - pubs.rsc.org
Covering: up to 2016 Antimycin-type depsipeptides are a family of natural products with
great structural diversity and outstanding biological activities. These compounds have …

Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds

J Rocha-Martin, C Harrington, ADW Dobson, F O'Gara - Marine drugs, 2014 - mdpi.com
Marine microorganisms continue to be a source of structurally and biologically novel
compounds with potential use in the biotechnology industry. The unique physiochemical …

Regulation of specialised metabolites in Actinobacteria–expanding the paradigms

PA Hoskisson… - Environmental …, 2018 - Wiley Online Library
The increase in availability of actinobacterial whole genome sequences has revealed huge
numbers of specialised metabolite biosynthetic gene clusters, encoding a range of bioactive …

The Interaction Mechanism of Picolinamide Fungicide Targeting on the Cytochrome bc1 Complex and Its Structural Modification

Y Dong, B Li, MX Yin, Z Liu, Y Niu, QY Wu… - Journal of Agricultural …, 2024 - ACS Publications
Picolinamide fungicides, structurally related to UK-2A and antimycin-A, bind into the Qi-site
in the bc 1 complex. However, the detailed binding mode of picolinamide fungicides remains …