Epilepsy is a serious neurological disorder characterized by abnormal, recurrent, and
synchronous discharges in the brain. Long-term recurrent seizure attacks can cause serious …

Contemporary microglia morphologies include ramified, activated and amoeboid, with the
morphology of microglia considered highly coupled to the cellular function. Rod microglia …

Extracellular vesicles (EVs) derived from human bone marrow mesenchymal stem cells
(hMSCs) have great promise as biologics to treat neurological and neurodegenerative …

Epilepsy, one of the most common neurological disorders worldwide, is characterized by
recurrent seizures and subsequent brain damage. Despite strong evidence supporting a …

Current anti-seizure drugs fail to control approximately 30% of epilepsies. Therefore, there is
a need to develop more effective anti-seizure drugs, and medicinal plants provide an …

Epilepsy is a chronic neurological complication characterized by unprovoked seizure
episodes due to the imbalance between excitatory and inhibitory neurons. The …

Extracellular ATP is a danger signal to the brain and contributes to neurodegeneration in
animal models of Alzheimer's disease through its extracellular catabolism by CD73 to …

Interneuron loss/dysfunction contributes to spontaneous recurrent seizures (SRS) in chronic
temporal lobe epilepsy (TLE), and interneuron grafting into the epileptic hippocampus …

Astroglial networks constitute a non-neuronal communication system in the brain and are
acknowledged modulators of synaptic plasticity. A sophisticated set of transmitter receptors …

Background Epilepsy affects∼ 60 million people worldwide. Most antiseizure medications in
the market act on voltage-gated sodium or calcium channels, indirectly modulating …