Resistance to therapeutic treatment and metastatic progression jointly determine a fatal
outcome of cancer. Cancer metastasis and therapeutic resistance are traditionally studied as …

Apoptosis is an evolutionarily conserved and tightly regulated cell death modality. It serves
important roles in physiology by sculpting complex tissues during embryogenesis and by …

Neurodegenerative diseases of the central nervous system progressively rob patients of
their memory, motor function, and ability to perform daily tasks. Advances in genetics and …

The receptor tyrosine kinase AXL, activated by a complex interaction between its ligand
growth arrest-specific protein 6 and phosphatidylserine, regulates various vital cellular …

Rationale: The mosquito-borne Zika virus (ZIKV) is now recognized as a blood-borne
pathogen, raising an important question about how the virus gets into human bloodstream …

Acute and chronic inflammatory responses in the lung are associated with the accumulation
of large quantities of immune and structural cells undergoing apoptosis, which need to be …

Purpose: Currently, an optimal therapeutic strategy comprising molecularly targeted agents
for treating EGFR-mutated non–small cell lung cancer (NSCLC) patients with acquired …

The numerous and diverse biological roles of Phosphatidylserine (PtdSer) are featured in
this special issue. This review will focus on PtdSer as a cofactor required for stimulating …

Questions in cancer have engaged systems biologists for decades. During that time, the
quantity of molecular data has exploded, but the need for abstractions, formal models, and …

Simple Summary Metastasis is a complex process that requires the acquisition of certain
traits by cancer cells as well as the cooperation of several non-neoplastic cells that populate …