Thiourea and Guanidine Derivatives as Antimalarial and Antimicrobial Agents §
A Mishra, S Batra - Current Topics in Medicinal Chemistry, 2013 - benthamdirect.com
Thiourea and guanidine substructural units are of significant importance as the compounds
containing these core units either in the open or the cyclic form are known to display an …
containing these core units either in the open or the cyclic form are known to display an …
Metallopharmaceuticals in therapy-a new horizon for scientific research
A Chylewska, M Biedulska… - Current Medicinal …, 2018 - ingentaconnect.com
Coordination chemistry offers much scope for the design of novel and therapeutic agents,
including metallopharmaceuticals. The widespread use of metal complexes as effective …
including metallopharmaceuticals. The widespread use of metal complexes as effective …
Design, synthesis, kinetic mechanism and molecular docking studies of novel 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical …
A series of novel 1-pentanoyl-3-arylthioureas was designed as new mushroom tyrosinase
inhibitors and free radical scavengers. The title compounds were obtained in excellent yield …
inhibitors and free radical scavengers. The title compounds were obtained in excellent yield …
Synthesis and in vitro urease inhibitory activity of N, N′-disubstituted thioureas
Abstract Thiourea derivatives (1–38) were synthesized and evaluated for their urease
inhibition potential. The synthetic compounds showed a varying degree of in vitro urease …
inhibition potential. The synthetic compounds showed a varying degree of in vitro urease …
Synthesis, cytotoxicity and antimicrobial activity of thiourea derivatives incorporating 3-(trifluoromethyl) phenyl moiety
A Bielenica, J Stefańska, K Stępień… - European Journal of …, 2015 - Elsevier
A total of 31 of thiourea derivatives was prepared reacting 3-(trifluoromethyl) aniline and
commercial aliphatic and aromatic isothiocyanates. The yields varied from 35% to 82%. All …
commercial aliphatic and aromatic isothiocyanates. The yields varied from 35% to 82%. All …
Fluorinated quaternary chitosan derivatives: Synthesis, characterization, antibacterial activity, and killing kinetics
Chitosan has become an established platform biopolymer with applications in biomedical
engineering, nanomedicine, and the development of new materials with improved solubility …
engineering, nanomedicine, and the development of new materials with improved solubility …
Isoprenyl-thiourea and urea derivatives as new farnesyl diphosphate analogues: Synthesis and in vitro antimicrobial and cytotoxic activities
A series of new isoprenyl-thiourea and urea derivatives were synthesized by the reaction of
alkyl or aryl isothiocyanate or isocyanate and primary amines. The structures of the …
alkyl or aryl isothiocyanate or isocyanate and primary amines. The structures of the …
Monodentate coordination of N-[di (phenyl/ethyl) carbamothioyl] benzamide ligands: synthesis, crystal structure and catalytic oxidation property of Cu (I) complexes
New four-coordinated tetrahedral copper (I) complexes have been synthesized from the
reactions between [CuCl2 (PPh3) 2] and N-(diphenylcarbamothioyl) benzamide (HL1) or N …
reactions between [CuCl2 (PPh3) 2] and N-(diphenylcarbamothioyl) benzamide (HL1) or N …
New substituted benzoylthiourea derivatives: from design to antimicrobial applications
The increasing threat of antimicrobial resistance to all currently available therapeutic agents
has urged the development of novel antimicrobials. In this context, a series of new …
has urged the development of novel antimicrobials. In this context, a series of new …
Synthesis, structures and antibacterial activities of benzoylthiourea derivatives and their complexes with cobalt
W Yang, H Liu, M Li, F Wang, W Zhou, J Fan - Journal of inorganic …, 2012 - Elsevier
Four new thiocarbonyl fluorobenzamides and their complexes with cobalt have been
synthesized and characterized by elemental analysis, FTIR, and 1H NMR. Five crystal …
synthesized and characterized by elemental analysis, FTIR, and 1H NMR. Five crystal …