Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …

The clinical successes in immunotherapy have been both astounding and at the same time
unsatisfactory. Countless patients with varied tumor types have seen pronounced clinical …

The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and is
strongly associated with adverse outcomes, including an increased risk of chronic kidney …

Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Choices have consequences. Immune cells survey and migrate throughout the body and
sometimes take residence in niche environments with distinct communities of cells …

Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly
understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse …

There is a growing interest in understanding tissue organization, homeostasis, and
inflammation. However, despite an abundance of data, the organizing principles of tissue …

For infectious-disease outbreaks, clinical solutions typically focus on efficient pathogen
destruction. However, the COVID-19 pandemic provides a reminder that infectious diseases …

Influenza virus affects the respiratory tract by direct viral infection or by damage from the
immune system response. In humans, the respiratory epithelium is the only site where the …