As an essential nutrient element, phosphorus (P) is primarily acquired and translocated as
inorganic phosphate (Pi) by plant roots. Pi is often sequestered in the soil and becomes …

Combinatorial substitution of phosphate groups on the inositol ring gives rise to a plethora of
inositol phosphates (InsPs) and inositol pyrophosphates (PP-InsPs). These small molecules …

Eukaryotic cells control inorganic phosphate to balance its role as essential macronutrient
with its negative bioenergetic impact on reactions liberating phosphate. Phosphate …

Precise regulation of intracellular phosphate (Pi) is critical for cellular function, with
xenotropic and polytropic retrovirus receptor 1 (XPR1) serving as the sole Pi exporter in …

Many proteins involved in eukaryotic phosphate homeostasis are regulated by SPX
domains. In yeast, the vacuolar transporter chaperone (VTC) complex contains two such …

Inositol pyrophosphates (PP-InsPs) constitute a group of highly charged messengers, which
regulate central biological processes in health and disease, such as cellular phosphate and …

Technical challenges have to date prevented a complete profiling of the levels of myo-
inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) in mammalian tissues. Here, we …

The combinatorial phosphorylation of myo-inositol results in the generation of different
inositol phosphates (InsPs), of which phytic acid (InsP6) is the most abundant species in …

The soil contributes to the main pool of essential mineral nutrients for plants. These mineral
nutrients are critical elements for the building blocks of plant biomolecules, play fundamental …

Inositol pyrophosphates (PP-InsPs), derivatives of inositol hexakisphosphate (phytic acid,
InsP6) or lower inositol polyphosphates, are energy-rich signaling molecules that have …