Universal vaccines and vaccine platforms to protect against influenza viruses in humans and agriculture

DS Rajão, DR Pérez - Frontiers in microbiology, 2018 - frontiersin.org
Influenza virus infections pose a significant threat to public health due to annual seasonal
epidemics and occasional pandemics. Influenza is also associated with significant economic …

Seasonal influenza vaccine in immunocompromised persons

M Bosaeed, D Kumar - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Immunocompromised persons are at high risk of complications from influenza infection. This
population includes those with solid organ transplants, hematopoietic stem cell transplants …

Strategic and scientific contributions of human challenge trials for vaccine development: facts versus fantasy

YN Abo, E Jamrozik, JS McCarthy… - The Lancet Infectious …, 2023 - thelancet.com
The unprecedented speed of delivery of SARS-CoV-2 pandemic vaccines has redefined the
limits for all vaccine development. Beyond the aspirational 100-day timeline for tomorrow's …

[HTML][HTML] Modulation of innate immune responses by the influenza A NS1 and PA-X proteins

A Nogales, L Martinez-Sobrido, DJ Topham… - Viruses, 2018 - mdpi.com
Influenza A viruses (IAV) can infect a broad range of animal hosts, including humans. In
humans, IAV causes seasonal annual epidemics and occasional pandemics, representing a …

Effectiveness of influenza vaccination in preventing hospitalization due to influenza in children: a systematic review and meta-analysis

NL Boddington, I Pearson, H Whitaker… - Clinical Infectious …, 2021 - academic.oup.com
This systematic review assesses the literature for estimates of influenza vaccine
effectiveness (IVE) against laboratory-confirmed influenza-associated hospitalization in …

[HTML][HTML] Novel approaches for the development of live attenuated influenza vaccines

P Blanco-Lobo, A Nogales, L Rodríguez… - Viruses, 2019 - mdpi.com
Influenza virus still represents a considerable threat to global public health, despite the
advances in the development and wide use of influenza vaccines. Vaccination with …

Immunogenicity and safety of inactivated quadrivalent influenza vaccine compared with the trivalent vaccine for influenza infection: an overview of systematic reviews

RL Carregaro, ANCP Roscani, ACS Raimundo… - BMC infectious …, 2023 - Springer
Background Influenza infection is a highly preventable transmissible viral disease
associated with mild upper respiratory symptoms and more severe conditions such as lethal …

Live attenuated and inactivated influenza vaccine effectiveness

JR Chung, B Flannery, CS Ambrose, RE Bégué… - …, 2019 - publications.aap.org
BACKGROUND: Researchers in observational studies of vaccine effectiveness (VE) in
which they compared quadrivalent live attenuated vaccine (LAIV4) and inactivated influenza …

End-of-season influenza vaccine effectiveness in adults and children, United Kingdom, 2016/17

R Pebody, F Warburton, J Ellis, N Andrews… - …, 2017 - pmc.ncbi.nlm.nih.gov
Introduction The United Kingdom is in the fourth season of introducing a universal childhood
influenza vaccine programme. The 2016/17 season saw early influenza A (H3N2) virus …

Live attenuated influenza vaccine (LAIV): recent effectiveness results from the USA and implications for LAIV programmes elsewhere

R Pebody, J McMenamin, H Nohynek - Archives of disease in …, 2018 - adc.bmj.com
The USA has a long-standing paediatric influenza vaccination programme, including use of
live attenuated influenza vaccine (LAIV). Following US evidence of apparent lack of vaccine …