The role of ferroptosis and cuproptosis in curcumin against hepatocellular carcinoma
Z Liu, H Ma, Z Lai - Molecules, 2023 - mdpi.com
Background: Among cancer-related deaths, hepatocellular carcinoma (HCC) ranks fourth,
and traditional Chinese medicine (TCM) treatment is an important complementary …
and traditional Chinese medicine (TCM) treatment is an important complementary …
Nuclei on the rise: when nuclei-based methods meet next-generation sequencing
In the last decade, we have witnessed an upsurge in nuclei-based studies, particularly
coupled with next-generation sequencing. Such studies aim at understanding the molecular …
coupled with next-generation sequencing. Such studies aim at understanding the molecular …
[HTML][HTML] THBS1-Mediated Degradation of Collagen via the PI3K/AKT Pathway Facilitates the Metastasis and Poor Prognosis of OSCC
Z Wen, Y Zhang, X Wang, Y Wu, J Mao, Q Li… - International Journal of …, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) is a prevalent form of malignant tumor, characterized
by a persistently high incidence and mortality rate. The extracellular matrix (ECM) plays a …
by a persistently high incidence and mortality rate. The extracellular matrix (ECM) plays a …
[HTML][HTML] Differentially expressed genes regulating glutathione metabolism, protein-folding, and unfolded protein response in pancreatic β-cells in type 2 diabetes …
E Klyosova, I Azarova, S Buikin… - International Journal of …, 2023 - mdpi.com
Impaired redox homeostasis in the endoplasmic reticulum (ER) may contribute to proinsulin
misfolding and thus to activate the unfolded protein response (UPR) and apoptotic …
misfolding and thus to activate the unfolded protein response (UPR) and apoptotic …
Serum/Plasma Proteome in Non-Malignant Liver Disease
L Fu, N Guldiken, K Remih, AS Karl… - International Journal of …, 2024 - mdpi.com
The liver is the central metabolic organ and produces 85–90% of the proteins found in
plasma. Accordingly, the plasma proteome is an attractive source of liver disease …
plasma. Accordingly, the plasma proteome is an attractive source of liver disease …
The impact of fiber source on digestive function, fecal microbiota, and immune response in adult dogs
M Montserrat-Malagarriga, L Castillejos, A Salas-Mani… - Animals, 2024 - mdpi.com
Simple Summary Dietary fiber has been widely recognized to have a profound impact on gut
microbiota and health. However, the ideal fiber intake in dogs still needs to be determined …
microbiota and health. However, the ideal fiber intake in dogs still needs to be determined …
Multi-omics profiling of hypertrophic cardiomyopathy reveals altered mechanisms in mitochondrial dynamics and excitation–contraction coupling
J Moore, J Ewoldt, G Venturini, AC Pereira… - International journal of …, 2023 - mdpi.com
Hypertrophic cardiomyopathy is one of the most common inherited cardiomyopathies and a
leading cause of sudden cardiac death in young adults. Despite profound insights into the …
leading cause of sudden cardiac death in young adults. Despite profound insights into the …
[HTML][HTML] Comprehensive analysis of PANoptosis-related gene signature of ulcerative colitis
JM Wang, J Yang, WY **a, YM Wang, YB Zhu… - International Journal of …, 2023 - mdpi.com
Accumulating evidence shows that the abnormal increase in the mortality of intestinal
epithelial cells (IECs) caused by apoptosis, pyroptosis, and necroptosis is closely related to …
epithelial cells (IECs) caused by apoptosis, pyroptosis, and necroptosis is closely related to …
[HTML][HTML] Definition of the neurotoxicity-associated metabolic signature triggered by berberine and other respiratory chain inhibitors
To characterize the hits from a phenotypic neurotoxicity screen, we obtained transcriptomics
data for valinomycin, diethylstilbestrol, colchicine, rotenone, 1-methyl-4-phenylpyridinium …
data for valinomycin, diethylstilbestrol, colchicine, rotenone, 1-methyl-4-phenylpyridinium …
[HTML][HTML] Ferroptosis inducers upregulate PD-L1 in recurrent triple-negative breast cancer
C Desterke, Y **ang, R Elhage, C Duruel, Y Chang… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is characterized by a quick and high
rate of recurrence. The benefits from neo-adjuvant chemotherapy associated with anti-PDL1 …
rate of recurrence. The benefits from neo-adjuvant chemotherapy associated with anti-PDL1 …