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Blockade of spinal α5-GABAA receptors differentially reduces reserpine-induced fibromyalgia-type pain in female rats
E Yarim, EJ Rodríguez-Palma… - European Journal of …, 2019 - Elsevier
The role of spinal α 5 subunit-containing GABA A (α 5-GABA A) receptors in chronic pain is
controversial. The purpose of this study was to investigate the participation of spinal α 5 …
controversial. The purpose of this study was to investigate the participation of spinal α 5 …
Current ion channel-targeted drugs and potential of venom-derived peptides as a therapeutic new modality
T Okada, H Taira, T Kimura - Venoms and Toxins, 2022 - benthamdirect.com
Ion channel function is essential for maintaining life and is involved in various physiological
activities. However, various factors such as heredity, aging, wounding, and diseases can …
activities. However, various factors such as heredity, aging, wounding, and diseases can …
Effects of α5 GABAA receptor modulation on social interaction, memory, and neuroinflammation in a mouse model of Alzheimer's disease
J Aranđelović, A Santrač, B Batinić… - CNS Neuroscience …, 2022 - Wiley Online Library
Aims GABAergic modulation involved in cognitive processing appears to be substantially
changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to …
changed in Alzheimer's disease (AD). In a widely used 5xFAD model of AD, we aimed to …
Positive modulation of α5 GABAA receptors in preadolescence prevents reduced locomotor response to amphetamine in adult female but not male rats prenatally …
B Batinić, A Santrač, I Jančić, G Li, A Vidojević… - International Journal of …, 2017 - Elsevier
We previously demonstrated that lipopolysaccharide (LPS) administered intraperitoneally
(ip) to pregnant Wistar rat dams, at embryonic days 15 and 16 (E15/16), induced a decrease …
(ip) to pregnant Wistar rat dams, at embryonic days 15 and 16 (E15/16), induced a decrease …
Abnormalities of Neurotransmission in Drug Addiction
Substance use disorders are prevalent and severe conditions associated with numerous
health, social, and economic harms. While the neurobiological mechanisms are still not fully …
health, social, and economic harms. While the neurobiological mechanisms are still not fully …
Repeated assessment of anxiety-like behavior in mice: a new tool with increasedreliability and consistency
Anxiety is a debilitating disorder with high prevalence and co-morbidity across multiple
psychiatric diseases. Evidence from both clinical and preclinical studies suggest that the …
psychiatric diseases. Evidence from both clinical and preclinical studies suggest that the …