Mercapto-substituted 1, 2, 4-triazoles are very interesting compounds as they play an
important role in chemopreventive and chemotherapeutic effects on cancer. In recent …

Triazoles are nitrogen‐bearing heterocycles. In the last few decades, researchers have
focused on fused heterocycles, as they have better pharmacological effect compared to …

The development of new approaches for the synthesis of new bioactive heterocyclic
derivatives is of the utmost importance for pharmaceutical industry. In this regard, the …

A series of novel hydrazinecarbothioamide, 1, 2, 4-triazole-3-thione, 4-thiazolidinone and 1,
3, 4-oxadiazole derivatives were synthesized and evaluated for their cytotoxic activity …

Breast cancer remains a major global health issue, particularly affecting women and
contributing significantly to mortality rates. Current treatments for estrogen receptor‐positive …

The essential enzyme cyclin-dependent kinase 2 (CDK2) is a promising target for anticancer
drug development due to its pivotal role in regulating the cell cycle. This study aimed to …

Aim: This study focuses on advancing green chemistry in anticancer drug discovery,
particularly through the synthesis of azine derivatives with a naphthalene core using CS …

Microwave-assisted synthesis of some novel compounds, namely, 3-(2-methyl-1 H-indol-3-
yl)-6-aryl-[1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazoles 5a, b was accomplished via …

Green synthesis using L-proline as an organocatalyst is crucial due to its reusability, mild
conditions, clean reactions, easy workup, high purity, short reaction times, and high yields …

A series of novel hydrazinecarbothioamide (5a, c, f), 4‐thiazolidinone (6a‐e), and 1, 2, 4‐
triazole‐3‐thione (7a‐d) were designed and synthesized. The structural elucidations of the …