Candida albicans cell-type switching and functional plasticity in the mammalian host
SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
The spectrum of fungi that infects humans
JR Köhler, A Casadevall… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …
Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism
K Pande, C Chen, SM Noble - Nature genetics, 2013 - nature.com
Abstract Among∼ 5,000,000 fungal species, C. albicans is exceptional in its lifelong
association with humans, either within the gastrointestinal microbiome or as an invasive …
association with humans, either within the gastrointestinal microbiome or as an invasive …
Sexual reproduction and the evolution of microbial pathogens
J Heitman - Current Biology, 2006 - cell.com
Three common systemic human fungal pathogens—Cryptococcus neoformans, Candida
albicans and Aspergillus fumigatus—have retained all the machinery to engage in sexual …
albicans and Aspergillus fumigatus—have retained all the machinery to engage in sexual …
White-Opaque Switching in Natural MTLa/α Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis, and Sex
J **
FC Odds, AD Davidson, MD Jacobsen… - Journal of clinical …, 2006 - Am Soc Microbiol
We typed 165 Candida albicans isolates from 44 different sources by multilocus sequence
ty** (MLST) and ABC ty** of rRNA genes and determined their homozygosity or …
ty** (MLST) and ABC ty** of rRNA genes and determined their homozygosity or …
Sex and virulence of human pathogenic fungi
K Nielsen, J Heitman - Advances in genetics, 2007 - Elsevier
Over the past decade, opportunistic fungal infectious diseases have increased in prevalence
as the population of immunocompromised individuals escalated due to HIV/AIDS and …
as the population of immunocompromised individuals escalated due to HIV/AIDS and …