The isocoumarins are naturally occurring lactones that constitute an important class of
natural products exhibiting an array of biological activities. A wide variety of these lactones …

Homocoupling of weakly coordinating sulfoxonium ylides was accomplished via ruthenium
(II) catalyzed C− H activation process. This strategy provides a convenient, efficient and step …

An efficient and robust protocol for the preparation of 3-substituted isocoumarins via
palladium-catalyzed nucleophilic addition/oxidative annulation of bromoalkynes with …

Eleven oxazolone derivatives were synthesized and characterized by 1H NMR, EI, IR and
UV spectroscopic and CHN analysis. Three compounds, 4-[(E)-(4-nitrophenyl) methylidene] …

Eucommia ulmoides Oliver is a traditional medicinal plant of China, and it is one of the main
sources of chlorogenic acid. Chlorogenic acid is an ester of caffeic acid, quinic acid, and a …

A novel and highly efficient strategy for the synthesis of isocoumarins and phthalides
through a palladium (0)-catalyzed reaction incorporating tert-butyl isocyanide has been …

A series of 15 previously reported N4-substituted isatin-3-thiosemicarbazones 3a-o has
been screened for cytotoxic, antibacterial, antifungal and urease inhibitory activities …

A Ru (II)-catalyzed C–H bond activation/annulation of N-iminopyridinium ylides with
sulfoxonium ylides has been developed for the synthesis of diverse functionalized …

4-Chloroisocoumarins can be conveniently prepared from 2-alkynylaryloate esters via the
activation of alkynes by electrophilic chlorine, generated in situ from N-chlorosuccinimide …

Herein, we report a facile and proficient protocol for the synthesis of 4‐bromoisocoumarins
through brominative annulation of 2‐alkynylaryloate esters with in situ generated …