Microfluidic multiplexing in bioanalyses

MK Araz, AM Tentori, AE Herr - Journal of Laboratory …, 2013 - journals.sagepub.com
The importance of biological assays spans from clinical diagnostics to environmental
monitoring. Simultaneous detection of multiple analytes enhances the efficacy of bioassays …

[LLIBRE][B] CRC concise encyclopedia of nanotechnology

BI Kharisov, OV Kharissova, U Ortiz-Mendez - 2016 - books.google.com
The book examines the design, application, and utilization of devices, techniques, and
technologies critical to research at the atomic, molecular, and macromolecular levels …

Microfluidic linear hydrogel array for multiplexed single nucleotide polymorphism (SNP) detection

YK Jung, J Kim, RA Mathies - Analytical Chemistry, 2015 - ACS Publications
A PDMS-based microfluidic linear hydrogel array is developed for multiplexed single
nucleotide polymorphism (SNP) detection. A sequence of three-dimensional (3D) hydrogel …

Microfluidic hydrogel arrays for direct genoty** of clinical samples

YK Jung, J Kim, RA Mathies - Biosensors and Bioelectronics, 2016 - Elsevier
A microfluidic hydrogel DNA microarray is developed to overcome the limitations of
conventional planar microarrays such as low sensitivity, long overnight hybridization time …

A polymer Lab-on-a-Chip for genetic analysis using the arrayed primer extension on microarray chips

SL Marasso, D Mombello, M Cocuzza… - Biomedical …, 2014 - Springer
In this work a polymer lab-on-a-chip (LOC), fabricated through MEMS technology, was
employed to execute a genetic protocol for the Single Nucleotide Polymorphisms (SNPs) …

Shrinking hydrogel‐DNA spots generates 3D microdots arrays

GC Le Goff, LJ Blum… - Macromolecular …, 2013 - Wiley Online Library
This report describes a straightforward approach for the achievement of sub‐100
micrometers size hydrogel dots supporting DNA immobilization. Hydrogel‐DNA spots are …

Chimeric RNA–DNA molecular beacons for quantification of nucleic acids, single nucleotide polymophisms, and nucleic acid damage

AF El-Yazbi, GR Loppnow - Analytical chemistry, 2013 - ACS Publications
Single nucleotide polymorphisms (SNPs) are the main cause for variations in the human
genome. DNA lesions, such as cyclobutane pyrimidine dimers (CPDs),[6–4] pyrimidine …

Polyplex formation influences release mechanism of mono-and di-valent ions from phosphorylcholine group bearing hydrogels

AN Wilson, M Blenner, A Guiseppi-Elie - Polymers, 2014 - mdpi.com
The release of monovalent potassium and divalent calcium ions from zwitterionic
phosphorylcholine containing poly (2-hydroxyethyl methacrylate)(pHEMA)-based hydrogels …

Microfluidic devices with permeable polymer barriers for capture and transport of biomolecules and cells

HS Lee, WK Chu, K Zhang, X Huang - Lab on a Chip, 2013 - pubs.rsc.org
We report a method for fabricating permeable polymer microstructure barriers in
polydimethylsiloxane (PDMS) microfluidic devices and the use of the devices to capture and …

Easy daylight fabricated hydrogel array for colorimetric DNA analysis

A Beyer, S Pollok, A Berg, K Weber… - Macromolecular …, 2014 - Wiley Online Library
The fabrication of 3D hydrogel microarrays for DNA analytics that allow simple visual signal
readout for on‐site applications is described. A convenient one‐step polymerization of the …