Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Nanotheranostics for personalized medicine

TH Kim, S Lee, X Chen - Expert review of molecular diagnostics, 2013 - Taylor & Francis
Nanotheranostics, the integration of diagnostic and therapeutic function in one system using
the benefits of nanotechnology, is extremely attractive for personalized medicine. Because …

Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons

PS Sheeran, SH Luois, LB Mullin, TO Matsunaga… - Biomaterials, 2012 - Elsevier
Recently, an interest has developed in designing biomaterials for medical ultrasonics that
can provide the acoustic activity of microbubbles, but with improved stability in vivo and a …

Release of photoactivatable drugs from plasmonic nanoparticles for targeted cancer therapy

YL Luo, YS Shiao, YF Huang - ACS nano, 2011 - ACS Publications
Chemotherapy is an important modality in cancer treatment. The major challenges of recent
works are to improve drug loading, increase selectivity to target cells, and control the precise …

Nanomaterial-based activatable imaging probes: from design to biological applications

J Li, F Cheng, H Huang, L Li, JJ Zhu - Chemical Society Reviews, 2015 - pubs.rsc.org
Activatable imaging probes as alternatives to “always on” imaging probes have attracted
more and more attention due to their improved sensitivity and specificity. They are commonly …

Urchin‐Shaped Manganese Oxide Nanoparticles as pH‐Responsive Activatable T1 Contrast Agents for Magnetic Resonance Imaging

T Kim, EJ Cho, Y Chae, M Kim, A Oh, J **… - Angewandte Chemie …, 2011 - infona.pl
Image enhancement: Core–shell MnO@ Mn 3 O 4 urchin‐shaped nanoparticles can be
synthesized by means of an anisotropic etching process and used as a pH‐activatable T 1 …

Delivery of cancer therapeutics using nanotechnology

EK Lim, E Jang, K Lee, S Haam, YM Huh - Pharmaceutics, 2013 - mdpi.com
Nanoparticles have been investigated as drug carriers, because they provide a great
opportunity due to their advantageous features:(i) various formulations using …

Radionuclide‐activated nanomaterials and their biomedical applications

CA Ferreira, D Ni, ZT Rosenkrans… - Angewandte Chemie …, 2019 - Wiley Online Library
Radio‐nanomedicine, or the use of radiolabeled nanoparticles in nuclear medicine, has
attracted much attention in the last few decades. Since the discovery of Cerenkov radiation …

[HTML][HTML] Dual-responsive molecular probe for tumor targeted imaging and photodynamic therapy

X Meng, Y Yang, L Zhou, Y Lv, S Li, Y Wu, M Zheng… - Theranostics, 2017 - ncbi.nlm.nih.gov
The precision oncology significantly relies on the development of multifunctional agents to
integrate tumor targeting, imaging and therapeutics. In this study, a first small-molecule …

Self-quenched gold nanoclusters for turn-on fluorescence imaging of intracellular glutathione

C Dai, C Yang, X Yan - Nano Research, 2018 - Springer
Activatable fluorescence nanoprobes with only one kind of nanomaterial that can act as both
the energy donor and acceptor simultaneously are scarce, but highly desirable for …