Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …

For the last five decades, science has managed to delineate the mechanisms by which
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …

Background Many studies report smaller hippocampal and amygdala volumes in
posttraumatic stress disorder (PTSD), but findings have not always been consistent. Here …

Music is a universal feature of human societies, partly owing to its power to evoke strong
emotions and influence moods. During the past decade, the investigation of the neural …

Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …

Child maltreatment is a robust risk factor for internalizing and externalizing psychopathology
in children and adolescents. We examined the role of disruptions in emotion regulation …

Posttraumatic stress disorder (PTSD) is associated with regional alterations in brain
structure and function that are hypothesized to contribute to symptoms and cognitive deficits …

Post-traumatic stress disorder (PTSD) is the only major mental disorder for which a cause is
considered to be known: that is, an event that involves threat to the physical integrity of …

How do adverse childhood experiences get 'under the skin'and influence health outcomes
through the life-course? Research reviewed here suggests that adverse childhood …

Anxiety and depression are the most frequently diagnosed psychological diseases showing
a high co-morbidity. They have a severe impact on the lives of the persons concerned. Many …