Review of signaling pathways governing MSC osteogenic and adipogenic differentiation
AW James - Scientifica, 2013 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …
Natural history of mesenchymal stem cells, from vessel walls to culture vessels
Mesenchymal stem/stromal cells (MSCs) can regenerate tissues by direct differentiation or
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …
Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
INTRODUCTION Fibroblasts are the predominant cell type that synthesizes and remodels
the extracellular matrix in organs during both embryonic and adult life and are central to the …
the extracellular matrix in organs during both embryonic and adult life and are central to the …
Radiation-induced skin fibrosis: pathogenesis, current treatment options, and emerging therapeutics
Radiotherapy (RT) has become an indispensable part of oncologic treatment protocols for a
range of malignancies. However, a serious adverse effect of RT is radiodermatitis; almost …
range of malignancies. However, a serious adverse effect of RT is radiodermatitis; almost …
The role of endoglin and its soluble form in pathogenesis of preeclampsia
G Margioula-Siarkou, C Margioula-Siarkou… - Molecular and Cellular …, 2022 - Springer
Preeclampsia remains till today a leading cause of maternal and fetal morbidity and
mortality. Pathophysiology of the disease is not yet fully elucidated, though it is evident that it …
mortality. Pathophysiology of the disease is not yet fully elucidated, though it is evident that it …
Endoglin: beyond the endothelium
MJA Schoonderwoerd, MJTH Goumans… - Biomolecules, 2020 - mdpi.com
Endoglin, a type-III accessory receptor for the Transforming Growth Factor (TGF)-β
superfamily pathway, is known for its crucial role during angiogenesis. Extensive work has …
superfamily pathway, is known for its crucial role during angiogenesis. Extensive work has …
Bone marrow aspirate concentrate quality is affected by age and harvest site
Purpose To compare the number and properties of bone marrow stromal cells (BMSCs)
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …
Diabetes impairs the angiogenic potential of adipose-derived stem cells by selectively depleting cellular subpopulations
Introduction Pathophysiologic changes associated with diabetes impair new blood vessel
formation and wound healing. Mesenchymal stem cells derived from adipose tissue (ASCs) …
formation and wound healing. Mesenchymal stem cells derived from adipose tissue (ASCs) …
Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells
Advanced age is associated with an increased risk of vascular morbidity, attributable in part
to impairments in new blood vessel formation. Mesenchymal stem cells (MSCs) have …
to impairments in new blood vessel formation. Mesenchymal stem cells (MSCs) have …
TGF-β and mesenchymal stromal cells in regenerative medicine, autoimmunity and cancer
V de Araújo Farias, AB Carrillo-Gálvez, F Martin… - Cytokine & Growth …, 2018 - Elsevier
Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …