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Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …
decade. Their multilineage differentiation potentials and immunomodulatory properties have …
Review of signaling pathways governing MSC osteogenic and adipogenic differentiation
Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …
Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
INTRODUCTION Fibroblasts are the predominant cell type that synthesizes and remodels
the extracellular matrix in organs during both embryonic and adult life and are central to the …
the extracellular matrix in organs during both embryonic and adult life and are central to the …
Radiation-induced skin fibrosis: pathogenesis, current treatment options, and emerging therapeutics
Radiotherapy (RT) has become an indispensable part of oncologic treatment protocols for a
range of malignancies. However, a serious adverse effect of RT is radiodermatitis; almost …
range of malignancies. However, a serious adverse effect of RT is radiodermatitis; almost …
Natural history of mesenchymal stem cells, from vessel walls to culture vessels
Mesenchymal stem/stromal cells (MSCs) can regenerate tissues by direct differentiation or
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …
The role of endoglin and its soluble form in pathogenesis of preeclampsia
G Margioula-Siarkou, C Margioula-Siarkou… - Molecular and cellular …, 2022 - Springer
Preeclampsia remains till today a leading cause of maternal and fetal morbidity and
mortality. Pathophysiology of the disease is not yet fully elucidated, though it is evident that it …
mortality. Pathophysiology of the disease is not yet fully elucidated, though it is evident that it …
Unveiling heterogeneity in MSCs: Exploring marker-based strategies for defining MSC subpopulations
S Chen, B Liang, J Xu - Journal of Translational Medicine, 2024 - Springer
Mesenchymal stem/stromal cells (MSCs) represent a heterogeneous cell population
distributed throughout various tissues, demonstrating remarkable adaptability to …
distributed throughout various tissues, demonstrating remarkable adaptability to …
Bone marrow aspirate concentrate quality is affected by age and harvest site
Purpose To compare the number and properties of bone marrow stromal cells (BMSCs)
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …
Endoglin: beyond the endothelium
Endoglin, a type-III accessory receptor for the Transforming Growth Factor (TGF)-β
superfamily pathway, is known for its crucial role during angiogenesis. Extensive work has …
superfamily pathway, is known for its crucial role during angiogenesis. Extensive work has …
TGF-β and mesenchymal stromal cells in regenerative medicine, autoimmunity and cancer
Multipotent mesenchymal stromal cells (MSCs) represent a promising cell-based therapy in
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …
regenerative medicine and for the treatment of inflammatory/autoimmune diseases …