[HTML][HTML] The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's disease

Y Ren, A Savadlou, S Park, P Siska, JR Epp… - Frontiers in …, 2023‏ - Elsevier
Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence
in women compared with men. Treatments aimed at improving pathology in AD remain …

Association between social integration and risk of dementia: A systematic review and meta‐analysis of longitudinal studies

S Wang, A Molassiotis, C Guo… - Journal of the …, 2023‏ - Wiley Online Library
Background Dementia is an emerging public health issue. Growing evidence emerged on
the association between social integration and the risk of dementia. However, the magnitude …

Social isolation, social support, and loneliness and their relationship with cognitive health and dementia

J Joyce, J Ryan, A Owen, J Hu… - … Journal of Geriatric …, 2022‏ - Wiley Online Library
Background Poor social health is prevalent in older adults and may be associated with
worse cognition, and increased dementia risk. The aim of this study was to determine …

COVID-19-related social support service closures and mental well-being in older adults and those affected by dementia: a UK longitudinal survey

C Giebel, D Pulford, C Cooper, K Lord, J Shenton… - BMJ open, 2021‏ - bmjopen.bmj.com
Background The COVID-19 pandemic has had a major impact on delivery of social support
services. This might be expected to particularly affect older adults and people living with …

[HTML][HTML] Impacts of low-cost robotic pets for older adults and people with dementia: sco** review

WQ Koh, FXH Ang, D Casey - JMIR rehabilitation and assistive …, 2021‏ - rehab.jmir.org
Background: Older adults and people with dementia are particularly vulnerable to social
isolation. Social robots, including robotic pets, are promising technological interventions that …

Frailty Trajectories Preceding Dementia in the US and UK

DD Ward, JP Flint, TJ Littlejohns, IF Foote… - JAMA …, 2025‏ - jamanetwork.com
Importance An accessible marker of both biological age and dementia risk is crucial to
advancing dementia prevention and treatment strategies. Although frailty is a candidate for …

Adverse childhood experiences and cognitive function in adulthood: examining the roles of depressive symptoms and inflammation in a prospective cohort study

E Lowry, A McInerney, N Schmitz… - Social psychiatry and …, 2022‏ - Springer
Abstract Purpose Adverse childhood experiences (ACEs) have been associated with
cognitive decline in adulthood. However, the underlying mechanisms implicated remain …

The molecular effects of environmental enrichment on Alzheimer's disease

AKY Liew, CH Teo, T Soga - Molecular neurobiology, 2022‏ - Springer
Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Potential neurobiological links between social isolation and Alzheimer's disease risk

E Drinkwater, C Davies… - European Journal of …, 2022‏ - Wiley Online Library
It is estimated that 40% of dementia cases could be prevented by modification of lifestyle
factors that associate with disease risk. One of these potentially modifiable lifestyle factors is …

Identifying predictors of self-perceptions of aging based on a range of cognitive, physical, and mental health indicators: Twenty-year longitudinal findings from the ILSE …

S Sabatini, JS Siebert, M Diehl, A Brothers… - Psychology and …, 2022‏ - psycnet.apa.org
Research exploring whether health predicts self-perceptions of aging (SPA) has mostly
focused on single predictors and has been hampered by short observational intervals. We …