Nanoparticles: Taking a unique position in medicine
The human nature of curiosity, wonder, and ingenuity date back to the age of humankind. In
parallel with our history of civilization, interest in scientific approaches to unravel …
parallel with our history of civilization, interest in scientific approaches to unravel …
Combretastatins: an overview of structure, probable mechanisms of action and potential applications
Combretastatins are a class of closely related stilbenes (combretastatins A),
dihydrostilbenes (combretastatins B), phenanthrenes (combretastatins C) and macrocyclic …
dihydrostilbenes (combretastatins B), phenanthrenes (combretastatins C) and macrocyclic …
Strategies targeting tumor immune and stromal microenvironment and their clinical relevance
The critical role of tumor microenvironment (TME) in tumor initiation and development has
been well-recognized after more than a century of studies. Numerous therapeutic …
been well-recognized after more than a century of studies. Numerous therapeutic …
A glance over doxorubicin based-nanotherapeutics: From proof-of-concept studies to solutions in the market
Cancer is one of the leading causes of death worldwide and, as such, efforts are being done
to find new chemotherapeutic drugs or, alternatively, novel approaches for the delivery of old …
to find new chemotherapeutic drugs or, alternatively, novel approaches for the delivery of old …
Nanogel-incorporated injectable hydrogel for synergistic therapy based on sequential local delivery of combretastatin-A4 phosphate (CA4P) and doxorubicin (DOX)
Drug combination therapies employing dual-drug delivery systems offer an effective
approach to reduce disadvantages of single-drug therapy, such as high dose and easy …
approach to reduce disadvantages of single-drug therapy, such as high dose and easy …
Recent advances in co-delivery nanosystems for synergistic action in cancer treatment
Nanocarrier delivery systems have been widely studied to carry unique or dual chemical
drugs. The major challenge of chemotherapies is to overcome the multidrug-resistance …
drugs. The major challenge of chemotherapies is to overcome the multidrug-resistance …
Combination of nanotechnology with vascular targeting agents for effective cancer therapy
R Jahanban‐Esfahlan, K Seidi… - Journal of cellular …, 2018 - Wiley Online Library
As a young science, nanotechnology promptly integrated into the current oncology practice.
Accordingly, various nanostructure particles were developed to reduce drug toxicity and …
Accordingly, various nanostructure particles were developed to reduce drug toxicity and …
Nanoparticle-based combination drug delivery systems for synergistic cancer treatment
Despite being a leading cause of death worldwide, cancer remains difficult to treat due to the
development of drug resistance and severe adverse effects associated with conventional …
development of drug resistance and severe adverse effects associated with conventional …
Polymer-mediated penetration-independent cancer therapy
J Ding, X Feng, Z Jiang, W Xu, H Guo… - …, 2019 - ACS Publications
The development of polymer-based drug delivery systems provides efficient modalities for
cancer therapy. Most of the polymer pharmaceuticals target cancer cells directly, but the …
cancer therapy. Most of the polymer pharmaceuticals target cancer cells directly, but the …
Liver-targeted liposomes for codelivery of curcumin and combretastatin A4 phosphate: preparation, characterization, and antitumor effects
H Jiang, ZP Li, GX Tian, RY Pan, CM Xu… - International Journal …, 2019 - Taylor & Francis
Background Recent efforts have been focused on combining two or more therapeutic
approaches with different mechanisms to enhance antitumor therapy. Moreover, nanosize …
approaches with different mechanisms to enhance antitumor therapy. Moreover, nanosize …