[HTML][HTML] Gut microbiota–derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis

D Li, Y Lu, S Yuan, X Cai, Y He, J Chen, Q Wu… - The American journal of …, 2022 - Elsevier
ABSTRACT Background Trimethylamine-N-oxide (TMAO) is a gut microbiota–derived
metabolite produced from dietary nutrients. Many studies have discovered that circulating …

Contribution of trimethylamine N-oxide (TMAO) to chronic inflammatory and degenerative diseases

LA Constantino-Jonapa, Y Espinoza-Palacios… - Biomedicines, 2023 - mdpi.com
Trimethylamine N-oxide (TMAO) is a metabolite produced by the gut microbiota and has
been mainly associated with an increased incidence of cardiovascular diseases (CVDs) in …

TMAO as a potential biomarker and therapeutic target for chronic kidney disease: A review

Y Zixin, C Lulu, Z **angchang, F Qing… - Frontiers in …, 2022 - frontiersin.org
The gut microbiota and its metabolites have become a hotspot of recent research.
Trimethylamine N-oxide (TMAO) metabolized by the gut microbiota is closely related to …

Can diet modulate trimethylamine N-oxide (TMAO) production? What do we know so far?

KS Coutinho-Wolino, LFM de F. Cardozo… - European journal of …, 2021 - Springer
Abstract Background Trimethylamine N-oxide (TMAO) is a metabolite that has attracted
attention due to its positive association with several chronic non-communicable diseases …

Microbiota effect on trimethylamine N-oxide production: from cancer to fitness—A practical preventing recommendation and therapies

E Tacconi, G Palma, D De Biase, A Luciano, M Barbieri… - Nutrients, 2023 - mdpi.com
Trimethylamine N-oxide (TMAO) is a microbial metabolite derived from nutrients, such as
choline, L-carnitine, ergothioneine and betaine. Recently, it has come under the spotlight for …

Concomitant memantine and Lactobacillus plantarum treatment attenuates cognitive impairments in APP/PS1 mice

QJ Wang, YE Shen, X Wang, S Fu, X Zhang… - Aging (albany …, 2020 - pmc.ncbi.nlm.nih.gov
Trimethylamine-N-oxide (TMAO) is a gut microbial metabolite that promotes Alzheimer's
disease (AD) progression. Given that probiotics can alleviate AD symptoms by inhibiting the …

Trimethylamine N-oxide in cardiovascular disease: Pathophysiology and the potential role of statins

F Latif, A Mubbashir, MS Khan, Z Shaikh, A Memon… - Life Sciences, 2024 - Elsevier
Cardiovascular diseases are one of the leading causes of mortality and morbidity worldwide,
with the total number of cases increasing to 523 million in 2019. Despite the advent of new …

[HTML][HTML] Fasting-mimicking diet reduces trimethylamine N-oxide levels and improves serum biochemical parameters in healthy volunteers

M Videja, E Sevostjanovs, S Upmale-Engela… - Nutrients, 2022 - mdpi.com
Elevated plasma levels of trimethylamine N-oxide (TMAO) have been proposed as a diet-
derived biomarker of cardiometabolic disease risk. Caloric restriction is the most common …

Targeting the gut microbiota by Asian and Western dietary constituents: a new avenue for diabetes

AR Conteh, R Huang - Toxicology research, 2020 - academic.oup.com
Increasing numerous diabetes annually is a great concern in public health globally. Gut
microbiota recently has been suggested to be an emerging organ acting as a critical …

Nutraceuticals and herbal food supplements for weight loss: is there a prebiotic role in the mechanism of action?

A Bertuccioli, M Cardinali, M Biagi, S Moricoli… - Microorganisms, 2021 - mdpi.com
Numerous nutraceuticals and botanical food supplements are used with the intention of
modulating body weight. A recent review examined the main food supplements used in …