Advances and perspectives in organic sonosensitizers for sonodynamic therapy

X **ng, S Zhao, T Xu, L Huang, Y Zhang, M Lan… - Coordination Chemistry …, 2021 - Elsevier
Sonodynamic therapy (SDT), which involves a combination of low-intensity ultrasound (US)
and a chemical sonosensitizer, has emerged as a promising minimally invasive and …

Supramolecular cancer nanotheranostics

J Zhou, L Rao, G Yu, TR Cook, X Chen… - Chemical Society …, 2021 - pubs.rsc.org
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …

Integration of TADF photosensitizer as “electron pump” and BSA as “electron reservoir” for boosting type I photodynamic therapy

W Chen, Z Wang, M Tian, G Hong, Y Wu… - Journal of the …, 2023 - ACS Publications
Type I photosensitization provides an effective solution to the problem of unsatisfactory
photodynamic therapeutic (PDT) effects caused by the tumor hypoxia. The challenge in the …

[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

Nanotechnology for multimodal synergistic cancer therapy

W Fan, B Yung, P Huang, X Chen - Chemical reviews, 2017 - ACS Publications
The complexity, diversity, and heterogeneity of tumors seriously undermine the therapeutic
potential of treatment. Therefore, the current trend in clinical research has gradually shifted …

Nanostructured particles assembled from natural building blocks for advanced therapies

Y Ju, H Liao, JJ Richardson, J Guo… - Chemical Society …, 2022 - pubs.rsc.org
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

T Tian, HX Zhang, CP He, S Fan, YL Zhu, C Qi… - Biomaterials, 2018 - Elsevier
The safe and effective delivery of drugs is a major obstacle in the treatment of ischemic
stroke. Exosomes hold great promise as an endogenous drug delivery nanosystem for the …

Analysis of nanoparticle delivery to tumours

S Wilhelm, AJ Tavares, Q Dai, S Ohta, J Audet… - Nature reviews …, 2016 - nature.com
Targeting nanoparticles to malignant tissues for improved diagnosis and therapy is a
popular concept. However, after surveying the literature from the past 10 years, only …

Light‐triggered in situ gelation to enable robust photodynamic‐immunotherapy by repeated stimulations

Z Meng, X Zhou, J Xu, X Han, Z Dong… - Advanced …, 2019 - Wiley Online Library
Photodynamic therapy (PDT) has shown the potential of triggering systemic antitumor
immune responses. However, while the oxygen‐deficient hypoxic tumor microenvironment …

Intelligent Albumin-MnO2 Nanoparticles as pH-/H2 O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy.

Q Chen, L Feng, J Liu, W Zhu, Z Dong… - … (Deerfield Beach, Fla.), 2016 - europepmc.org
A unique type of pH/H2 O2 dual-responsive intelligent nanoscale delivery system based on
albumin-coated MnO2 is presented, which is capable of modulating the tumor …