Hard and soft protein corona of nanomaterials: Analysis and relevance

R García-Álvarez, M Vallet-Regí - Nanomaterials, 2021 - mdpi.com
Upon contact with a biological milieu, nanomaterials tend to interact with biomolecules
present in the media, especially proteins, leading to the formation of the so-called “protein …

[HTML][HTML] In vitro approaches to assess the hazard of nanomaterials

B Drasler, P Sayre, KG Steinhäuser, A Petri-Fink… - NanoImpact, 2017 - Elsevier
The rapid development of engineered nanomaterials demands for a fast and reliable
assessment of their health hazard potential. A plethora of experimental approaches have …

The coupling of rotational and translational dynamics for rapid diffusion of nanorods in macromolecular networks

B Xue, Y Liu, Y Tian, P Yin - Nature Communications, 2024 - nature.com
The rod-like viruses show anomalously rapid diffusion in bio-tissue networks originated from
the rotation-facilitated transportation; however, the experimental investigation of the …

Techniques for the experimental investigation of the protein corona

C Carrillo-Carrion, M Carril, WJ Parak - Current Opinion in Biotechnology, 2017 - Elsevier
Highlights•Direct versus indirect analysis of the protein corona.•In situ measurements of
protein corona versus measurements requiring purification.•Characterization apart from …

In situ detection of the protein corona in complex environments

M Carril, D Padro, P Del Pino, C Carrillo-Carrion… - Nature …, 2017 - nature.com
Colloidal nanoparticles (NPs) are a versatile potential platform for in vivo nanomedicine.
Inside blood circulation, NPs may undergo drastic changes, such as by formation of a …

In situ characterization techniques of protein corona around nanomaterials

F Fu, D Crespy, K Landfester, S Jiang - Chemical Society Reviews, 2024 - pubs.rsc.org
Nanoparticles (NPs) inevitably interact with proteins upon exposure to biological fluids,
leading to the formation of an adsorption layer known as the “protein corona”. This corona …

Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …

V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …

Fungal synthesis of size-defined nanoparticles

A Zielonka, M Klimek-Ochab - Advances in natural Sciences …, 2017 - iopscience.iop.org
Fungi with metabolic capacities can efficiently synthesize a wide range of nanoparticles
(NPs). This biotransformation process and its product have extensive applications especially …

Plasma protein adsorption and biological identity of systemically administered nanoparticles

D Chen, S Ganesh, W Wang, M Amiji - Nanomedicine, 2017 - Taylor & Francis
Although a variety of nanoparticles (NPs) have been used for drug delivery applications,
their surfaces are immediately covered by plasma protein corona upon systemic …

In situ characterization of the protein corona of nanoparticles in vitro and in vivo

PL Latreille, JM Rabanel, M Le Goas… - Advanced …, 2022 - Wiley Online Library
A new theoretical framework that enables the use of differential dynamic microscopy (DDM)
in fluorescence imaging mode to quantify in situ protein adsorption onto nanoparticles (NP) …