Cellular components of the tumour microenvironment (TME) are recognized to regulate the
hallmarks of cancers including tumour proliferation, angiogenesis, invasion, and metastasis …

Polycomb group proteins regulate chromatin structure and have an important regulatory role
on gene expression in various cell types. Two polycomb group complexes (Polycomb …

Purpose Expansion of CD8+ cytotoxic Tlymphocytes is a prerequisite for anti-cancer
immune activity and has gained interest in the era of immune checkpoint therapy. Methods …

Background Many previous studies have revealed that tumour-infiltrating lymphocytes (TILs)
are significantly associated with prognosis in various tumours. However, this finding remains …

Background: Early-stage non-small cell lung cancer (NSCLC) patients carry significant risk
of recurrence post-surgery. In-depth characterization of the immune tumor microenvironment …

Despite the success of therapies in lung cancer, more studies of new biomarkers for patient
selection are urgently needed. The present study aims to analyze the role of galectin‐3 (GAL …

Background Low pH suppresses the proliferation and cytotoxic activity of CD8+ cytotoxic
and natural killer lymphocytes. The hypoxia-regulated transmembrane protein, carbonic …

Purpose The aim of this study was to investigate the degree of infiltration of CD8+ tumor-
infiltrating lymphocytes (TILs) including high and low density in lung sarcomatoid carcinoma …

Background: Studies about CD8+ FOXP3+ T cells as a subtype of regulatory T cells (Treg
cells) in non-small cell lung cancer (NSCLC) are few. Associations among the …

Abstract Background & Aims Adjuvant cytokine‐induced killer (CIK) cells treatment has
shown potential in reducing the recurrence rate and prolonging the survival of patients with …