The effects of childhood maltreatment on brain structure, function and connectivity
Maltreatment-related childhood adversity is the leading preventable risk factor for mental
illness and substance abuse. Although the association between maltreatment and …
illness and substance abuse. Although the association between maltreatment and …
Nutrition and brain development in early life
Presented here is an overview of the pathway from early nutrient deficiency to long-term
brain function, cognition, and productivity, focusing on research from low-and middle-income …
brain function, cognition, and productivity, focusing on research from low-and middle-income …
Effects of early life stress on cognitive and affective function: an integrated review of human literature
P Pechtel, DA Pizzagalli - Psychopharmacology, 2011 - Springer
Rationale The investigation of putative effects of early life stress (ELS) in humans on later
behavior and neurobiology is a fast develo** field. While epidemiological and …
behavior and neurobiology is a fast develo** field. While epidemiological and …
The neurobiological consequences of early stress and childhood maltreatment
Early severe stress and maltreatment produces a cascade of neurobiological events that
have the potential to cause enduring changes in brain development. These changes occur …
have the potential to cause enduring changes in brain development. These changes occur …
Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
A critical period for social experience–dependent oligodendrocyte maturation and myelination
Early social isolation results in adult behavioral and cognitive dysfunction that correlates
with white matter alterations. However, how social deprivation influences myelination and …
with white matter alterations. However, how social deprivation influences myelination and …
The role of early life stress as a predictor for alcohol and drug dependence
MA Enoch - Psychopharmacology, 2011 - Springer
Rationale Genetic and environmental influences on the development of alcohol and drug
dependence are equally important. Exposure to early life stress, that is unfortunately …
dependence are equally important. Exposure to early life stress, that is unfortunately …
Let's call the whole thing off: evaluating gender and sex differences in executive function
The executive functions allow for purposeful, deliberate, and intentional interactions with the
world—attention and focus, impulse control, decision making, and working memory. These …
world—attention and focus, impulse control, decision making, and working memory. These …
Childhood trauma associated with smaller hippocampal volume in women with major depression
OBJECTIVE: Smaller hippocampal volume has been reported only in some but not all
studies of unipolar major depressive disorder. Severe stress early in life has also been …
studies of unipolar major depressive disorder. Severe stress early in life has also been …
Brain structures in pediatric maltreatment-related posttraumatic stress disorder: a sociodemographically matched study
MD De Bellis, MS Keshavan, H Shifflett, S Iyengar… - Biological …, 2002 - Elsevier
BACKGROUND: Previous investigations suggest that maltreated children evidence
alterations of chemical mediators of stress and adverse brain development. Previous …
alterations of chemical mediators of stress and adverse brain development. Previous …