Harnessing the plant microbiome for sustainable crop production

S Compant, F Cassan, T Kostić, L Johnson… - Nature Reviews …, 2024 - nature.com
Global research on the plant microbiome has enhanced our understanding of the complex
interactions between plants and microorganisms. The structure and functions of plant …

A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome

CN Vassallo, CR Doering, ML Littlehale… - Nature …, 2022 - nature.com
The ancient, ongoing coevolutionary battle between bacteria and their viruses,
bacteriophages, has given rise to sophisticated immune systems including restriction …

Structure, functions, and diversity of the healthy human microbiome

T Ahrodia, S Das, S Bakshi, B Das - Progress in molecular biology and …, 2022 - Elsevier
Taxonomic composition and functional potency of microbes associated with different parts of
the human body have largely been explored by culture-independent metagenome …

Spatial map** of mobile genetic elements and their bacterial hosts in complex microbiomes

B Grodner, H Shi, O Farchione, AC Vill, I Ntekas… - Nature …, 2024 - nature.com
The exchange of mobile genetic elements (MGEs) facilitates the spread of functional traits
including antimicrobial resistance within bacterial communities. Tools to spatially map MGEs …

Phage therapy in Germany—update 2023

C Willy, JJ Bugert, AY Classen, L Deng, A Düchting… - Viruses, 2023 - mdpi.com
Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally
and in Germany. Here, we provide an overview of the current situation (2023) of applied …

[HTML][HTML] Emerging technologies in the study of the virome

SE Smith, W Huang, K Tiamani, M Unterer… - Current opinion in …, 2022 - Elsevier
Highlights•New amplification methods reduce biases caused by whole genome
amplification•Biases caused by assembly can be avoided using long-read …

Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection

S Luo, J Ru, MK Mirzaei, J Xue, X Peng, A Ralser… - Gut …, 2023 - Taylor & Francis
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. While
a close correlation between chronic Helicobacter pylori infection and CRC has been …

Microbiota-directed biotherapeutics: considerations for quality and functional assessment

EE Fekete, D Figeys, X Zhang - Gut Microbes, 2023 - Taylor & Francis
Mounting evidence points to causative or correlative roles of gut microbiome in the
development of a myriad of diseases ranging from gastrointestinal diseases, metabolic …

Advances and optimization strategies in bacteriophage therapy for treating inflammatory bowel disease

Y Li, X Li, H Duan, K Yang, J Ye - Frontiers in Immunology, 2024 - frontiersin.org
In the advancement of Inflammatory Bowel Disease (IBD) treatment, existing therapeutic
methods exhibit limitations; they do not offer a complete cure for IBD and can trigger adverse …

Bacteriophage-mediated manipulations of microbiota in gastrointestinal diseases

L El Haddad, JF Mendoza, C Jobin - Frontiers in Microbiology, 2022 - frontiersin.org
Although some gastrointestinal diseases could be managed using various antibiotics
regimen, this therapeutic approach lacks precision and damages the microbiota. Emerging …