Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research

X Tong, R Tang, M **ao, J Xu, W Wang… - Journal of hematology & …, 2022 - Springer
Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

Pyroptosis: mechanisms and diseases

P Yu, X Zhang, N Liu, L Tang, C Peng… - Signal transduction and …, 2021 - nature.com
Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

[HTML][HTML] Pyroptosis: a new frontier in cancer

Y Fang, S Tian, Y Pan, W Li, Q Wang, Y Tang… - Biomedicine & …, 2020 - Elsevier
Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …

A bibliometric analysis of pyroptosis from 2001 to 2021

D Ma, B Yang, B Guan, L Song, Q Liu, Y Fan… - Frontiers in …, 2021 - frontiersin.org
Background Pyroptosis is a new programmed cell death discovered in recent years.
Pyroptosis plays an important role in various diseases. Nevertheless, there are few …

Dietary flavonoid aglycones and their glycosides: Which show better biological significance?

J **ao - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. The natural flavonoids …

Advance on the Flavonoid C-glycosides and Health Benefits

J **ao, E Capanoglu, AR Jassbi… - Critical reviews in food …, 2016 - Taylor & Francis
The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. Almost all natural flavonoids …

The emerging role of pyroptosis in pediatric cancers: from mechanism to therapy

H Wang, X Zhou, C Li, S Yan, C Feng, J He… - Journal of hematology & …, 2022 - Springer
Pediatric cancers are the driving cause of death for children and adolescents. Due to safety
requirements and considerations, treatment strategies and drugs for pediatric cancers have …

Paraptosis: A non-classical paradigm of cell death for cancer therapy

C Xu, Y Lin, M Huang, X Zhang, P Wang… - Acta Pharmacologica …, 2024 - nature.com
Due to the sustained proliferative potential of cancer cells, inducing cell death is a potential
strategy for cancer therapy. Paraptosis is a mode of cell death characterized by endoplasmic …

Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with UCEC

J Liu, R Geng, S Ni, L Cai, S Yang, F Shao… - … Therapy-Nucleic Acids, 2022 - cell.com
Uterine corpus endometrial carcinoma (UCEC) is a malignant disease globally, and there is
no unified prognostic signature at present. In our study, two clusters were identified. Cluster …

Cancer-type-specific crosstalk between autophagy, necroptosis and apoptosis as a pharmacological target

F Radogna, M Dicato, M Diederich - Biochemical pharmacology, 2015 - Elsevier
Cell death plays an essential role in the development of organs, homeostasis, and cancer.
Apoptosis and programmed necrosis are two major types of cell death, characterized by …