Label-free microfluidic cell sorting and detection for rapid blood analysis

N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Recent developments in isolating methods for exosomes

J Gao, A Li, J Hu, L Feng, L Liu, Z Shen - Frontiers in bioengineering …, 2023 - frontiersin.org
Exosomes are the smallest extracellular vesicles that can be released by practically all cell
types, and range in size from 30 nm to 150 nm. As the major marker of liquid biopsies …

Label-free isolation of exosomes using microfluidic technologies

S Hassanpour Tamrin, A Sanati Nezhad, A Sen - ACS nano, 2021 - ACS Publications
Exosomes are cell-derived structures packaged with lipids, proteins, and nucleic acids. They
exist in diverse bodily fluids and are involved in physiological and pathological processes …

Recent microfluidic advances in submicron to nanoparticle manipulation and separation

S Hettiarachchi, H Cha, L Ouyang, A Mudugamuwa… - Lab on a Chip, 2023 - pubs.rsc.org
Manipulation and separation of submicron and nanoparticles are indispensable in many
chemical, biological, medical, and environmental applications. Conventional technologies …

Multiphysics microfluidics for cell manipulation and separation: a review

H Cha, H Fallahi, Y Dai, D Yuan, H An, NT Nguyen… - Lab on a Chip, 2022 - pubs.rsc.org
Multiphysics microfluidics, which combines multiple functional physical processes in a
microfluidics platform, is an emerging research area that has attracted increasing interest for …

Microfluidics for detection of exosomes and microRNAs in cancer: State of the art

SM Mousavi, SMA Mahdian, MS Ebrahimi… - … Therapy-Nucleic Acids, 2022 - cell.com
Exosomes are small extracellular vesicles with sizes ranging from 30–150 nanometers that
contain proteins, lipids, mRNAs, microRNAs, and double-stranded DNA derived from the …

Geometric structure design of passive label-free microfluidic systems for biological micro-object separation

H Tang, J Niu, H **, S Lin, D Cui - Microsystems & Nanoengineering, 2022 - nature.com
Passive and label-free microfluidic devices have no complex external accessories or
detection-interfering label particles. These devices are now widely used in medical and …

Emerging integrated SERS-microfluidic devices for analysis of cancer-derived small extracellular vesicles

L Ngo, A Tukova, A Hassanzadeh-Barforoushi… - Lab on a Chip, 2023 - pubs.rsc.org
Cancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer
vesicles secreted from cancer cells to the extracellular environment. They carry distinct …

Functional micro‐/nanomaterials for multiplexed biodetection

X Liu, W Wu, D Cui, X Chen, W Li - Advanced Materials, 2021 - Wiley Online Library
When analyzing biological phenomena and processes, multiplexed biodetection has many
advantages over single‐factor biodetection and is highly relevant to both human health …

Engineered exosomes for studies in tumor immunology

A Alptekin, M Parvin, HI Chowdhury… - Immunological …, 2022 - Wiley Online Library
Exosomes are a type of extracellular vesicle (EV) with diameters of 30–150 nm secreted by
most of the cells into the extracellular spaces and can alter the microenvironment through …