Abstract Measles, Nipah and Hendra viruses are severe human pathogens within the
Paramyxoviridae family. Their non-segmented, single-stranded, negative-sense RNA …

Protein aggregation is a widespread phenomenon implicated in debilitating diseases like
Alzheimer's, Parkinson's, and cataracts, presenting complex hurdles for the field of …

Protein aggregation is responsible for several degenerative conditions in humans, and it is
also a bottleneck in industrial protein production and storage of biotherapeutics …

The presence of insoluble protein deposits in tissues and organs is a hallmark of many
human pathologies. In addition, the formation of protein aggregates is considered one of the …

Prion-like domains (PrLDs) are intrinsically disordered regions (IDRs) of low sequence
complexity with a similar composition to yeast prion domains. PrLDs-containing proteins …

Protein and peptide aggregation has recently become one of the most studied biomedical
problems due to its central role in several neurodegenerative disorders and of …

Several databases collecting amyloidogenic regions have been released to provide
information on protein sequences able to form amyloid fibrils. However, most of these …

It is widely known that, in higher eukaryotes, the amyloid form of a number of proteins that
control neuronal activity leads to the shutdown of their function and toxicity, which causes …

Background Proteins self-organize in dynamic cellular environments by assembling into
reversible biomolecular condensates through liquid-liquid phase separation (LLPS). These …