Collagen-and hyaluronic acid-based hydrogels and their biomedical applications

Q Xu, JE Torres, M Hakim, PM Babiak, P Pal… - Materials Science and …, 2021 - Elsevier
Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Opportunities and challenges of nanomaterials in wound healing: Advances, mechanisms, and perspectives

W Fu, S Sun, Y Cheng, J Ma, Y Hu, Z Yang… - Chemical Engineering …, 2024 - Elsevier
Wound healing is an intricate process that involves interactions between various types of
cell and molecular mechanisms. When wounds fail to heal effectively or develop into chronic …

pH-switchable antimicrobial nanofiber networks of hydrogel eradicate biofilm and rescue stalled healing in chronic wounds

J Wang, XY Chen, Y Zhao, Y Yang, W Wang, C Wu… - Acs Nano, 2019 - ACS Publications
Biofilm infections can induce chronic inflammation and stall the normal orchestrated course
of wound-healing cascades. Herein, pH-switchable antimicrobial hydrogel with nanofiber …

Proline-dependent regulation of collagen metabolism

E Karna, L Szoka, TYL Huynh, JA Palka - Cellular and Molecular Life …, 2020 - Springer
This review is focused on recent data on the role of proline (Pro) in collagen biosynthesis
and cellular metabolism. It seems obvious that one of the main substrates for collagen …

Modification of chitosan using amino acids for wound healing purposes: A review

S Torkaman, H Rahmani, A Ashori, SHM Najafi - Carbohydrate polymers, 2021 - Elsevier
Chitosan, a well-known biopolymer due to its unique properties, has received considerable
attention as a result of the amine group activity that locates on the backbone of chitosan. To …

Main and minor types of collagens in the articular cartilage: the role of collagens in repair tissue evaluation in chondral defects

L Alcaide-Ruggiero, V Molina-Hernández… - International Journal of …, 2021 - mdpi.com
Several collagen subtypes have been identified in hyaline articular cartilage. The main and
most abundant collagens are type II, IX and XI collagens. The minor and less abundant …

Roles of PLODs in collagen synthesis and cancer progression

Y Qi, R Xu - Frontiers in cell and developmental biology, 2018 - frontiersin.org
Collagen is the major component of extracellular matrix. Collagen cross-link and deposition
depend on lysyl hydroxylation, which is catalyzed by procollagen-lysine, 2-oxoglutarate 5 …

Hydroxyproline in animal metabolism, nutrition, and cell signaling

S Hu, W He, G Wu - Amino Acids, 2022 - Springer
Abstract trans-4-Hydroxy-l-proline is highly abundant in collagen (accounting for about one-
third of body proteins in humans and other animals). This imino acid (loosely called amino …

PROLIDASE: A Review from Discovery to its Role in Health and Disease

I Eni-Aganga, ZM Lanaghan… - Frontiers in Molecular …, 2021 - frontiersin.org
Prolidase (peptidase D), encoded by the PEPD gene, is a ubiquitously expressed cytosolic
metalloproteinase, the only enzyme capable of cleaving imidodipeptides containing C …

Staphylococcus aureus biofilm infection compromises wound healing by causing deficiencies in granulation tissue collagen

S Roy, S Santra, A Das, S Dixith, M Sinha… - Annals of …, 2020 - journals.lww.com
Objective: The objective of this work was to causatively link biofilm properties of bacterial
infection to specific pathogenic mechanisms in wound healing. Background: Staphylococcus …