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Six shades of vascular smooth muscle cells illuminated by KLF4 (Krüppel-Like Factor 4)
C Yap, A Mieremet, CJM de Vries, D Micha… - … , and vascular biology, 2021 - ahajournals.org
Multiple layers of vascular smooth muscle cells (vSMCs) are present in blood vessels
forming the media of the vessel wall. vSMCs provide a vessel wall structure, enabling it to …
forming the media of the vessel wall. vSMCs provide a vessel wall structure, enabling it to …
Vascular smooth muscle cells in atherosclerosis: time for a re-assessment
Vascular smooth muscle cells (VSMCs) are key participants in both early and late-stage
atherosclerosis. VSMCs invade the early atherosclerotic lesion from the media, expanding …
atherosclerosis. VSMCs invade the early atherosclerotic lesion from the media, expanding …
Smooth muscle cell-driven vascular diseases and molecular mechanisms of VSMC plasticity
Vascular smooth muscle cells (VSMCs) are the major cell type in blood vessels. Unlike
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
many other mature cell types in the adult body, VSMC do not terminally differentiate but …
Cardiac-specific miRNA in cardiogenesis, heart function, and cardiac pathology (with focus on myocardial infarction)
Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …
Origin and differentiation of vascular smooth muscle cells
G Wang, L Jacquet, E Karamariti… - The Journal of …, 2015 - Wiley Online Library
Vascular smooth muscle cells (SMCs), a major structural component of the vessel wall, not
only play a key role in maintaining vascular structure but also perform various functions …
only play a key role in maintaining vascular structure but also perform various functions …
Hepatocyte-derived extracellular vesicles promote endothelial inflammation and atherogenesis via microRNA-1
Background & Aims Clinical evidence has indicated a close link between non-alcoholic fatty
liver disease (NAFLD) and cardiovascular disease (CVD). However, the underlying …
liver disease (NAFLD) and cardiovascular disease (CVD). However, the underlying …
Impact of miRNA in atherosclerosis
e160 Arterioscler Thromb Vasc Biol September 2018 were actively exported to the
cytoplasm with exportin-5 in a Ran-GTP–dependent manner. In the cytoplasm, the transition …
cytoplasm with exportin-5 in a Ran-GTP–dependent manner. In the cytoplasm, the transition …
Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation
The phenotype of vascular smooth muscle cells (VSMCs) is dynamically regulated in
response to various stimuli. In a cellular process known as phenotype switching, VSMCs …
response to various stimuli. In a cellular process known as phenotype switching, VSMCs …
microRNAs: important regulators of stem cells
N Li, B Long, W Han, S Yuan, K Wang - Stem cell research & therapy, 2017 - Springer
Stem cells are undifferentiated cells and have multi-lineage differentiation potential.
Generally, stem cells are classified into adult stem cells, embryonic stem cells (ESCs) and …
Generally, stem cells are classified into adult stem cells, embryonic stem cells (ESCs) and …
Down-regulation of Krüppel-like Factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth …
In the postnatal vasculature, fully differentiated and quiescent vascular smooth muscle cells
(VSMCs) in a" contractile" phenotype are required for the normal regulation of vascular tone …
(VSMCs) in a" contractile" phenotype are required for the normal regulation of vascular tone …