The aging process starts directly after birth and lasts for the entire lifespan; it manifests itself
with a decline in an organism's ability to adapt and is linked to the development of age …

Cancer patients are often diagnosed with venous thromboembolism (VTE), a cardiovascular
disease that substantially decreases their quality of life and survival rate. Haemostasis in …

MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
specific gene modifications. Platelets are the major source for circulating miRNAs, with …

Diabetic wound healing is an incompletely understood pathophysiological state. It
comprises a range of potentially devastating and common complications of diabetes mellitus …

For excluding deep-vein thrombosis (DVT), a negative D-dimer and low clinical probability
are used to rule out DVT. Circulating microRNAs (miRNAs) are stably present in the plasma …

Cancer-associated venous thrombosis (VTE) increases mortality and morbidity. However,
limited tools are available to identify high risk patients. Upon activation, neutrophils release …

Existing evidence suggests that in most cases antithrombin deficiency can be explained by
mutations in its gene, SERPINC 1. We investigated the molecular background of …

The haemostatic system is pivotal to maintaining vascular integrity. Multiple components
involved in blood coagulation have central functions in inflammation and immunity. A …

Background: During extracorporeal membrane oxygenation, the large contact surface
between the blood and the extracorporeal circuit causes a continuous activation of …

Neutrophil extracellular traps (NETs) represent an important link between inflammation and
thrombosis. Here, the present study aimed to investigate the influence of the NET …