The assembly of ribosomal subunits is a highly orchestrated process that involves a huge
cohort of accessory factors. Most eukaryotic ribosome biogenesis factors were first identified …

During the last ten years, developments in cryo–electron microscopy have transformed our
understanding of eukaryotic ribosome assembly. As a result, the field has advanced from a …

Simple Summary Cells need to produce ribosomes to sustain continuous proliferation and
expand in numbers, a feature that is even more prominent in uncontrollably proliferating …

The dysregulation of ribosome biogenesis is a hallmark of cancer, facilitating the adaptation
to altered translational demands essential for various aspects of tumor progression. This …

Different regions of RNA molecules can often engage in specific interactions with distinct
RNA-binding proteins (RBPs), giving rise to diverse modalities of RNA regulation and …

Eukaryotic ribosome assembly is a highly orchestrated process that involves over two
hundred protein factors. After early assembly events on nascent rRNA in the nucleolus, pre …

Cancer initiates as a consequence of genomic mutations and its subsequent progression
relies in part on increased production of ribosomes to maintain high levels of protein …

Chemical modifications of ribosomal RNAs (rRNAs) and proteins expand their topological
repertoire, and together with the plethora of bound ligands, fine-tune ribosomal function …

Polyamines are ubiquitous small organic cations, and their roles as regulators of several
cellular processes are widely recognized. They are implicated in the key stages of the fungal …

While microRNAs and other non-coding RNAs are the next frontier of novel regulators of
mammalian ribosome biogenesis (RB), a systematic exploration of microRNA-mediated RB …