Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

Obesity has been associated with oxidative stress. Obese patients are at increased risk for
diabetic cognitive dysfunction, indicating a pathological link between obesity, oxidative …

Lipids are the most abundant but poorly explored components of the human brain. Here, we
present a lipidome map of the human brain comprising 75 regions, including 52 neocortical …

Both the discovery of biomarkers of schizophrenia and the verification of biological
hypotheses of schizophrenia are an essential part of the process of understanding the …

Depression is one of the most common mental illnesses in modern society. In recent years,
several studies show that there are disturbances in lipid metabolism in depressed patients …

Despite loss of grey matter volume and emergence of distinct cognitive deficits in young
adults diagnosed with schizophrenia, current treatments for schizophrenia do not target …

Lysosomes are critical for cellular metabolism and are heterogeneously involved in various
cellular processes. The ability to measure lysosomal metabolic heterogeneity is essential for …

Background: Lipids are essential components of the structure and for the function of brain
cells. The intricate balance of lipids, including phospholipids, glycolipids, cholesterol …

Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …

Introduction Although researchers have done intensive research on depression, its
pathogenesis is still not fully explained. More and more evidence suggests that gut …