Chromatin-associated RNAs as facilitators of functional genomic interactions

X Li, XD Fu - Nature Reviews Genetics, 2019 - nature.com
Mammalian genomes are extensively transcribed, which produces a large number of both
coding and non-coding transcripts. Various RNAs are physically associated with chromatin …

Decoding protein–RNA interactions using CLIP-based methodologies

JS ** mouse cortex
T Sapir, A Kshirsagar, A Gorelik, T Olender… - Nature …, 2022 - nature.com
HNRNPU encodes the heterogeneous nuclear ribonucleoprotein U, which participates in
RNA splicing and chromatin organization. Microdeletions in the 1q44 locus encompassing …

Interchromosomal interactions: a genomic love story of kissing chromosomes

PG Maass, AR Barutcu, JL Rinn - Journal of Cell Biology, 2019 - rupress.org
Nuclei require a precise three-and four-dimensional organization of DNA to establish cell-
specific gene-expression programs. Underscoring the importance of DNA topology …

Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells

L Chang, M Li, S Shao, C Li, S Ai, B Xue, Y Hou… - Protein & …, 2022 - academic.oup.com
The eukaryotic genome is folded into higher-order conformation accompanied with
constrained dynamics for coordinated genome functions. However, the molecular machinery …