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[HTML][HTML] Is melatonin the “next vitamin D”?: a review of emerging science, clinical uses, safety, and dietary supplements
DM Minich, M Henning, C Darley, M Fahoum… - Nutrients, 2022 - mdpi.com
Melatonin has become a popular dietary supplement, most known as a chronobiotic, and for
establishing healthy sleep. Research over the last decade into cancer, Alzheimer's disease …
establishing healthy sleep. Research over the last decade into cancer, Alzheimer's disease …
[HTML][HTML] Amino acids in the regulation of aging and aging-related diseases
Amino acids are the building blocks of protein, but also play important cellular signaling
roles. The mechanisms through which altered levels of many amino acids are sensed and …
roles. The mechanisms through which altered levels of many amino acids are sensed and …
Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride‐induced liver fibrosis
JW Kang, JM Hong, SM Lee - Journal of pineal research, 2016 - Wiley Online Library
Liver fibrosis leads to liver cirrhosis and failure, and no effective treatment is currently
available. Growing evidence supports a link between mitochondrial dysfunction and liver …
available. Growing evidence supports a link between mitochondrial dysfunction and liver …
Polyunsaturated fatty acids metabolism, purine metabolism and inosine as potential independent diagnostic biomarkers for major depressive disorder in children and …
Major depressive disorder (MDD) in children and adolescents is a recurrent and disabling
condition globally but its pathophysiology remains poorly elucidated and there are limited …
condition globally but its pathophysiology remains poorly elucidated and there are limited …
Discovery and validation of plasma biomarkers for major depressive disorder classification based on liquid chromatography–mass spectrometry
X Liu, P Zheng, X Zhao, Y Zhang, C Hu… - Journal of proteome …, 2015 - ACS Publications
Major depressive disorder (MDD) is a debilitating mental disease with a pronounced impact
on the quality of life of many people; however, it is still difficult to diagnose MDD accurately …
on the quality of life of many people; however, it is still difficult to diagnose MDD accurately …
The role of melatonin, a multitasking molecule, in retarding the processes of ageing
Biological ageing is generally accompanied by a gradual loss of cellular functions and
physiological integrity of organ systems, the consequential enhancement of vulnerability …
physiological integrity of organ systems, the consequential enhancement of vulnerability …
Effects of resveratrol and other polyphenols on Sirt1: relevance to brain function during aging
Background: Classically the oxidative stress and more recently inflammatory processes
have been identified as the major causes of brain aging. Oxidative stress and inflammation …
have been identified as the major causes of brain aging. Oxidative stress and inflammation …
Protective effects of melatonin and mitochondria-targeted antioxidants against oxidative stress: a review
Oxidative damage is related to aging and a wide range of human disorders. Mitochondria
are in large part responsible for free radical production and they are also main targets of the …
are in large part responsible for free radical production and they are also main targets of the …
The neuroprotective effects of polyphenols, their role in innate immunity and the interplay with the microbiota
Neurodegenerative disorders, particularly in the elderly population, represent one of the
most pressing social and health-care problems in the world. Besides the well-established …
most pressing social and health-care problems in the world. Besides the well-established …
Adding fuel to the fire: the impact of stress on the ageing brain
Both ageing and chronic stress are associated with altered brain plasticity, dysregulation of
the immune system, and an increased risk of develo** brain disorders; all of which have …
the immune system, and an increased risk of develo** brain disorders; all of which have …