Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)

J Wu, X Wang, Q Wang, Z Lou, S Li, Y Zhu… - Chemical Society …, 2019 - pubs.rsc.org
Nanozymes are nanomaterials with enzyme-like characteristics (Chem. Soc. Rev., 2013, 42,
6060–6093). They have been developed to address the limitations of natural enzymes and …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Carbon nanozymes: enzymatic properties, catalytic mechanism, and applications

H Sun, Y Zhou, J Ren, X Qu - … Chemie International Edition, 2018 - Wiley Online Library
Nanozymes have advantages over natural enzymes, such as facile production on large
scale, long storage time, low costs, and high stability in harsh environments. Carbon …

Defect‐rich adhesive nanozymes as efficient antibiotics for enhanced bacterial inhibition

F Cao, L Zhang, H Wang, Y You… - Angewandte Chemie …, 2019 - Wiley Online Library
Nanozymes have emerged as a new generation of antibiotics with exciting broad‐spectrum
antimicrobial properties and negligible biotoxicities. However, their antibacterial efficacies …

Surface-enhanced Raman scattering active gold nanoparticles with enzyme-mimicking activities for measuring glucose and lactate in living tissues

Y Hu, H Cheng, X Zhao, J Wu, F Muhammad, S Lin… - ACS …, 2017 - ACS Publications
Gold nanoparticles (AuNPs) with simultaneous plasmonic and biocatalytic properties
provide a promising approach to develo** versatile bioassays. However, the combination …

Molecular imprinting on inorganic nanozymes for hundred-fold enzyme specificity

Z Zhang, X Zhang, B Liu, J Liu - Journal of the American Chemical …, 2017 - ACS Publications
Enzyme-mimicking nanomaterials (nanozymes) are more cost-effective and robust than
protein enzymes, but they lack specificity. Herein, molecularly imprinted polymers were …

Aptamer-modified Au nanoparticles: Functional nanozyme bioreactors for cascaded catalysis and catalysts for chemodynamic treatment of cancer cells

Y Ouyang, M Fadeev, P Zhang, R Carmieli, J Li… - ACS …, 2022 - ACS Publications
Polyadenine-stabilized Au nanoparticles (pA-AuNPs) reveal dual nanozyme catalytic
activities toward the H2O2-mediated oxidation of dopamine to aminochrome and toward the …

Chiral Molecule-mediated Porous CuxO Nanoparticle Clusters with Antioxidation Activity for Ameliorating Parkinson's Disease

C Hao, A Qu, L Xu, M Sun, H Zhang… - Journal of the …, 2018 - ACS Publications
Reactive oxygen species (ROS)-mediated mitochondrial dysfunction is one of the major
pathological mechanisms of Parkinson's disease. Using inorganic nanomaterials to …

Biomedical potential of nanozymes: Harnessing redox enzyme mimicry for theranostic applications

S Shahraki, E Vaziri, AA Saboury, K Fan - Coordination Chemistry Reviews, 2024 - Elsevier
Natural enzymes possess remarkable catalytic activity and substrate specificity, but their
limited environmental stability and high cost have prompted researchers to seek alternative …