Type 2 diabetes mellitus (T2DM) is still a global health problem. Current T2DM treatments
are limited to curing the symptoms and have not been able to restore insulin sensitivity in …

Diabetes is prevailing in pandemic proportions, as nearly half a billion population is affected
by diabetes worldwide. The expenditure on diabetes healthcare is estimated to grow to $845 …

Objectives: Describe the mechanism of action of sulfonylureas. Explain the potential adverse
effects of sulfonylureas. Review sulfonylurea overdoses and the treatment options available …

Fenpropathrin is a commonly used pesticide, which was ingested by humans through diet
and water. Gliquidone is a common hypoglycemic drug that diabetic patients need for long …

Glibenclamide is widely used and remains a cornerstone and an effective antihyperglycemic
drug. After the casual discovery of its hypoglycemic potential, this compound was introduced …

Acetylshikonin, a naphthoquinone derivative derived from Lithospermum erythrorhizon, has
been shown to have various pharmacological activities; however, its effect on diabetes has …

New compounds with promising antidiabetic activity were synthesized. For the first time, a
portion of the glibenclamide molecule was bound to a part of the core structure of …

Objectives Diabetes Mellitus (DM) is a global health concern that affects millions of people
globally. The present review aims to narrate the clinical guidelines and therapeutic …

Diabetes mellitus (DM) is a metabolic disease that causes disruption of spermatogenesis
due to decreased numbers of Sertoli cells and Leydig cells. The aim of this study was to …

Cardiovascular disease is a major comorbidity associated with diabetes mellitus. Various
antidiabetic drugs are currently used to treat type 2 diabetes mellitus and have varying …