A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Bone biomaterials and interactions with stem cells

C Gao, S Peng, P Feng, C Shuai - Bone research, 2017 - nature.com
Bone biomaterials play a vital role in bone repair by providing the necessary substrate for
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …

[HTML][HTML] The influence of nanotopography on cell behaviour through interactions with the extracellular matrix–A review

J Luo, M Walker, Y **ao, H Donnelly, MJ Dalby… - Bioactive materials, 2022 - Elsevier
Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Bioceramics to regulate stem cells and their microenvironment for tissue regeneration

Y Zhou, C Wu, J Chang - Materials Today, 2019 - Elsevier
Bioceramics have been used for the replacement and repair of damaged hard tissues for
about 50 years, in which the mechanical properties and biocompatibility of the materials are …

Photoactuating artificial muscles of motor amphiphiles as an extracellular matrix mimetic scaffold for mesenchymal stem cells

S Chen, L Yang, FKC Leung, T Kajitani… - Journal of the …, 2022 - ACS Publications
Mimicking the native extracellular matrix (ECM) as a cell culture scaffold has long attracted
scientists from the perspective of supramolecular chemistry for potential application in …

Pushing the natural frontier: Progress on the integration of biomaterial cues toward combinatorial biofabrication and tissue engineering

CF Guimarães, AP Marques, RL Reis - Advanced Materials, 2022 - Wiley Online Library
The engineering of fully functional, biological‐like tissues requires biomaterials to direct
cellular events to a near‐native, 3D niche extent. Natural biomaterials are generally seen as …

Delivering mechanical stimulation to cells: state of the art in materials and devices design

Y Zhang, P Habibovic - Advanced Materials, 2022 - Wiley Online Library
Biochemical signals, such as growth factors, cytokines, and transcription factors are known
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …

High-throughput routes to biomaterials discovery

F Soheilmoghaddam, M Rumble… - Chemical …, 2021 - ACS Publications
Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …

Synergistic effect of cell-derived extracellular matrices and topography on osteogenesis of mesenchymal stem cells

L Yang, L Ge, P van Rijn - ACS applied materials & interfaces, 2020 - ACS Publications
Cell-derived matrices (CDMs) are an interesting alternative to conventional sources of
extracellular matrices (ECMs) as CDMs mimic the natural ECM composition better and are …