The use of collagen-based materials in bone tissue engineering

L Fan, Y Ren, S Emmert, I Vučković… - International Journal of …, 2023 - mdpi.com
Synthetic bone substitute materials (BSMs) are becoming the general trend, replacing
autologous grafting for bone tissue engineering (BTE) in orthopedic research and clinical …

[HTML][HTML] Surface engineering of nanomaterials with polymers, biomolecules, and small ligands for nanomedicine

AM Díez-Pascual - Materials, 2022 - mdpi.com
Nanomedicine is a speedily growing area of medical research that is focused on develo**
nanomaterials for the prevention, diagnosis, and treatment of diseases. Nanomaterials with …

Gene-and RNAi-activated scaffolds for bone tissue engineering: Current progress and future directions

NZ Laird, TM Acri, K Tingle, AK Salem - Advanced drug delivery reviews, 2021 - Elsevier
Large bone defects are usually managed by replacing lost bone with non-biological
prostheses or with bone grafts that come from the patient or a donor. Bone tissue …

Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools

DL Puhl, D Mohanraj, DW Nelson, RJ Gilbert - Advanced drug delivery …, 2022 - Elsevier
Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …

Recent advances in gene therapy for bone tissue engineering

F Ranjbarnejad, M Khazaei, A Shahryari… - Journal of tissue …, 2022 - Wiley Online Library
Autografting, a major treatment for bone fractures, has potential risks related to the required
surgery and disease transmission. Bone morphogenetic proteins (BMPs) are the most …

Influence of biomimetically mineralized collagen scaffolds on bone cell proliferation and immune activation

L Bacakova, K Novotna, D Hadraba, J Musilkova… - Polymers, 2022 - mdpi.com
Collagen, as the main component of connective tissue, is frequently used in various tissue
engineering applications. In this study, porous sponge-like collagen scaffolds were prepared …

Growth Factor Delivery Using a Collagen Membrane for Bone Tissue Regeneration

T Takayama, K Imamura, S Yamano - Biomolecules, 2023 - mdpi.com
The use of biomaterials and bioactive agents has shown promise in bone defect repair,
leading to the development of strategies for bone regeneration. Various artificial …

Osteogenesis enhancement with 3D printed gene-activated sodium alginate scaffolds

M Khvorostina, A Mironov, I Nedorubova, T Bukharova… - Gels, 2023 - mdpi.com
Natural and synthetic hydrogel scaffolds containing bioactive components are increasingly
used in solving various tissue engineering problems. The encapsulation of DNA-encoding …

Mineralized vectors for gene therapy

TA Dick, ED Sone, H Uludağ - Acta biomaterialia, 2022 - Elsevier
There is an intense interest in develo** materials for safe and effective delivery of
polynucleotides using non-viral vectors. Mineralization of organic templates has long been …

Plasmid Encoding Mirna-200C Delivered by Caco3-Based Nanoparticles Enhances Rat Alveolar Bone Formation

MT Remy, Q Ding, T Krongbaramee, J Hu… - …, 2022 - Taylor & Francis
Aim: miRNAs have been shown to improve the restoration of craniofacial bone defects. This
work aimed to enhance transfection efficiency and miR-200c-induced bone formation in …