Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
K Devantier, VMS Kjær, S Griffin… - British Journal of …, 2024 - Wiley Online Library
Viroporins possess important potential as antiviral targets due to their critical roles during
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …
Revisiting respiratory syncytial virus's interaction with host immunity, towards novel therapeutics
Every year there are> 33 million cases of Respiratory Syncytial Virus (RSV)-related
respiratory infection in children under the age of five, making RSV the leading cause of …
respiratory infection in children under the age of five, making RSV the leading cause of …
Bacterial and viral coinfections with the human respiratory syncytial virus
The human respiratory syncytial virus (hRSV) is one of the leading causes of acute lower
respiratory tract infections in children under five years old. Notably, hRSV infections can give …
respiratory tract infections in children under five years old. Notably, hRSV infections can give …
How RSV proteins join forces to overcome the host innate immune response
T Van Royen, I Rossey, K Sedeyn, B Schepens… - Viruses, 2022 - mdpi.com
Respiratory syncytial virus (RSV) is the leading cause of severe acute lower respiratory tract
infections in infants worldwide. Although several pattern recognition receptors (PRRs) can …
infections in infants worldwide. Although several pattern recognition receptors (PRRs) can …
A respiratory syncytial virus vaccine based on the small hydrophobic protein ectodomain presented with a novel lipid-based formulation is highly immunogenic and …
Background Respiratory syncytial virus infection can cause lower respiratory tract infection
in older adults comparable to influenza, but no vaccines are available. Methods This was a …
in older adults comparable to influenza, but no vaccines are available. Methods This was a …
GBP5 is an interferon-induced inhibitor of respiratory syncytial virus
Z Li, X Qu, X Liu, C Huan, H Wang, Z Zhao… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT Guanylate binding protein 5 (GBP5) belongs to the GTPase subfamily, which is
mainly induced by interferon gamma (IFN-γ) and is involved in many important cellular …
mainly induced by interferon gamma (IFN-γ) and is involved in many important cellular …
A review of therapeutics in clinical development for respiratory syncytial virus and influenza in children
EG Nicholson, FM Munoz - Clinical therapeutics, 2018 - Elsevier
Purpose Respiratory syncytial virus (RSV) and influenza are important viral pathogens
worldwide. Children, in particular, bear considerable burdens of morbidity and mortality …
worldwide. Children, in particular, bear considerable burdens of morbidity and mortality …
Immunological features of respiratory syncytial virus-caused pneumonia—implications for vaccine design
E Rey-Jurado, AM Kalergis - International journal of molecular sciences, 2017 - mdpi.com
The human respiratory syncytial virus (hRSV) is the causative agent for high rates of
hospitalizations due to viral bronchiolitis and pneumonia worldwide. Such a disease is …
hospitalizations due to viral bronchiolitis and pneumonia worldwide. Such a disease is …
Global progress in clinical research on human respiratory syncytial virus vaccines
R Peng, C Chen, Q Chen, Y Zhang, R Huang… - Frontiers in …, 2024 - frontiersin.org
Human respiratory syncytial virus (hRSV) not only affects newborns but also older adults,
contributing to a substantial worldwide burden of disease. However, only three approved …
contributing to a substantial worldwide burden of disease. However, only three approved …
Modulation of host immunity by human respiratory syncytial virus virulence factors: a synergic inhibition of both innate and adaptive immunity
G Canedo-Marroquín, O Acevedo-Acevedo… - Frontiers in cellular …, 2017 - frontiersin.org
The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory
tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly …
tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly …